ACOT12 protein (Homo sapiens) - STRING network view

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Score

ACOT12

acyl-CoA thioesterase 12; Hydrolyzes acetyl-CoA to acetate and CoA (555 aa)

Predicted Functional Partners:

ACAT1

0.919

ALDH1B1

0.911

ALDH3A2

0.908

ACAT2

0.906

ACACB

0.902

ACACA

0.902

ENSG00000257767

0.900

ALDH7A1

0.900

ACYP2

0.900

ALDH9A1

0.900

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACACA	ACACB	ENSP00000344789	ENSP00000341044	acetyl-CoA carboxylase alpha	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	0.999
ACACA	ACAT1	ENSP00000344789	ENSP00000265838	acetyl-CoA carboxylase alpha	acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism	0.980
ACACA	ACAT2	ENSP00000344789	ENSP00000356015	acetyl-CoA carboxylase alpha	acetyl-CoA acetyltransferase 2	0.980
ACACA	ACOT12	ENSP00000344789	ENSP00000303246	acetyl-CoA carboxylase alpha	acyl-CoA thioesterase 12; Hydrolyzes acetyl-CoA to acetate and CoA	0.902
ACACA	ALDH1B1	ENSP00000344789	ENSP00000366927	acetyl-CoA carboxylase alpha	aldehyde dehydrogenase 1 family, member B1; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation	0.638
ACACA	ALDH3A2	ENSP00000344789	ENSP00000345774	acetyl-CoA carboxylase alpha	aldehyde dehydrogenase 3 family, member A2; Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid	0.633
ACACA	ALDH7A1	ENSP00000344789	ENSP00000387123	acetyl-CoA carboxylase alpha	aldehyde dehydrogenase 7 family, member A1; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism	0.659
ACACA	ALDH9A1	ENSP00000344789	ENSP00000346827	acetyl-CoA carboxylase alpha	aldehyde dehydrogenase 9 family, member A1; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction	0.636
ACACA	ENSG00000257767	ENSP00000344789	ENSP00000450353	acetyl-CoA carboxylase alpha	Uncharacterized protein	0.632
ACACB	ACACA	ENSP00000341044	ENSP00000344789	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	acetyl-CoA carboxylase alpha	0.999
ACACB	ACAT1	ENSP00000341044	ENSP00000265838	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism	0.979
ACACB	ACAT2	ENSP00000341044	ENSP00000356015	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	acetyl-CoA acetyltransferase 2	0.980
ACACB	ACOT12	ENSP00000341044	ENSP00000303246	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	acyl-CoA thioesterase 12; Hydrolyzes acetyl-CoA to acetate and CoA	0.902
ACACB	ALDH1B1	ENSP00000341044	ENSP00000366927	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	aldehyde dehydrogenase 1 family, member B1; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation	0.669
ACACB	ALDH3A2	ENSP00000341044	ENSP00000345774	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	aldehyde dehydrogenase 3 family, member A2; Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid	0.644
ACACB	ALDH7A1	ENSP00000341044	ENSP00000387123	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	aldehyde dehydrogenase 7 family, member A1; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism	0.632
ACACB	ALDH9A1	ENSP00000341044	ENSP00000346827	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	aldehyde dehydrogenase 9 family, member A1; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction	0.639
ACACB	ENSG00000257767	ENSP00000341044	ENSP00000450353	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	Uncharacterized protein	0.632
ACAT1	ACACA	ENSP00000265838	ENSP00000344789	acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism	acetyl-CoA carboxylase alpha	0.980
ACAT1	ACACB	ENSP00000265838	ENSP00000341044	acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	0.979

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