Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | ZNF804A | zinc finger protein 804A (1209 aa) | ||||||||||||
Predicted Functional Partners:
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 | MYT1L | myelin transcription factor 1-like; May function as a panneural transcription factor associated with neuronal differentiation. May play a role in the development of neurons and oligodendrogalia in the CNS (By similarity) (1184 aa) |
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0.866 | ||||||||||
 | HOXC8 | homeobox C8; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis (242 aa) |
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0.797 | ||||||||||
 | PRSS16 | protease, serine, 16 (thymus); Protease that may play a role in T-cell development (514 aa) |
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0.795 | ||||||||||
 | CSMD1 | CUB and Sushi multiple domains 1; Potential suppressor of squamous cell carcinomas (3564 aa) |
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0.703 | ||||||||||
 | CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit (2186 aa) |
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0.648 | ||||||||||
 | WBP1L | WW domain binding protein 1-like (363 aa) |
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0.636 | ||||||||||
 | HOXD8 | homeobox D8; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis (290 aa) |
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0.615 | ||||||||||
 | HOXB8 | homeobox B8; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis (243 aa) |
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0.615 | ||||||||||
 | ANK3 | ankyrin 3, node of Ranvier (ankyrin G); In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments (4377 aa) |
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0.583 | ||||||||||
 | C2orf80 | chromosome 2 open reading frame 80 (193 aa) |
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0.581 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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