node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C9orf85 | FRMD3 | ENSP00000334289 | ENSP00000303508 | chromosome 9 open reading frame 85 | FERM domain containing 3 | 0.501 |
CPVL | FRMD3 | ENSP00000265394 | ENSP00000303508 | carboxypeptidase, vitellogenic-like; May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation | FERM domain containing 3 | 0.599 |
FRMD3 | C9orf85 | ENSP00000303508 | ENSP00000334289 | FERM domain containing 3 | chromosome 9 open reading frame 85 | 0.501 |
FRMD3 | CPVL | ENSP00000303508 | ENSP00000265394 | FERM domain containing 3 | carboxypeptidase, vitellogenic-like; May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation | 0.599 |
FRMD3 | GNA11 | ENSP00000303508 | ENSP00000078429 | FERM domain containing 3 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class); Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C | 0.517 |
FRMD3 | GNAQ | ENSP00000303508 | ENSP00000286548 | FERM domain containing 3 | guanine nucleotide binding protein (G protein), q polypeptide; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity) | 0.522 |
FRMD3 | KIF27 | ENSP00000303508 | ENSP00000297814 | FERM domain containing 3 | kinesin family member 27; Plays an essential role in motile ciliogenesis (By similarity) | 0.651 |
FRMD3 | NPAP1 | ENSP00000303508 | ENSP00000333735 | FERM domain containing 3 | nuclear pore associated protein 1; May be involved in spermatogenesis | 0.686 |
FRMD3 | PSAT1 | ENSP00000303508 | ENSP00000365773 | FERM domain containing 3 | phosphoserine aminotransferase 1; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) | 0.599 |
FRMD3 | RASEF | ENSP00000303508 | ENSP00000365630 | FERM domain containing 3 | RAS and EF-hand domain containing; Binds predominantly GDP, and also GTP | 0.773 |
FRMD3 | SLC28A3 | ENSP00000303508 | ENSP00000365413 | FERM domain containing 3 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 3; Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2-1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3’-azido-3’-deoxythymidine (AZT), ribavirin and 3-deazauridine | 0.527 |
FRMD3 | TLE1 | ENSP00000303508 | ENSP00000365682 | FERM domain containing 3 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG | 0.547 |
GNA11 | FRMD3 | ENSP00000078429 | ENSP00000303508 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class); Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C | FERM domain containing 3 | 0.517 |
GNA11 | GNAQ | ENSP00000078429 | ENSP00000286548 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class); Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C | guanine nucleotide binding protein (G protein), q polypeptide; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity) | 0.900 |
GNA11 | RASEF | ENSP00000078429 | ENSP00000365630 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class); Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C | RAS and EF-hand domain containing; Binds predominantly GDP, and also GTP | 0.503 |
GNAQ | FRMD3 | ENSP00000286548 | ENSP00000303508 | guanine nucleotide binding protein (G protein), q polypeptide; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity) | FERM domain containing 3 | 0.522 |
GNAQ | GNA11 | ENSP00000286548 | ENSP00000078429 | guanine nucleotide binding protein (G protein), q polypeptide; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity) | guanine nucleotide binding protein (G protein), alpha 11 (Gq class); Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C | 0.900 |
GNAQ | RASEF | ENSP00000286548 | ENSP00000365630 | guanine nucleotide binding protein (G protein), q polypeptide; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity) | RAS and EF-hand domain containing; Binds predominantly GDP, and also GTP | 0.518 |
KIF27 | FRMD3 | ENSP00000297814 | ENSP00000303508 | kinesin family member 27; Plays an essential role in motile ciliogenesis (By similarity) | FERM domain containing 3 | 0.651 |
KIF27 | RASEF | ENSP00000297814 | ENSP00000365630 | kinesin family member 27; Plays an essential role in motile ciliogenesis (By similarity) | RAS and EF-hand domain containing; Binds predominantly GDP, and also GTP | 0.626 |