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DIEXF DIEXF FTSJ3 FTSJ3 WDR12 WDR12 RRS1 RRS1 UTP14A UTP14A UTP14C UTP14C NGDN NGDN MAK16 MAK16 RRP9 RRP9 DUS1L DUS1L RPL4 RPL4
"DUS1L" - dihydrouridine synthase 1-like (S. cerevisiae) in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small protein node
small nodes:
protein of unknown 3D structure
large protein node
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some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
DUS1Ldihydrouridine synthase 1-like (S. cerevisiae); Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) (473 aa)    
Predicted Functional Partners:
RPL4
ribosomal protein L4 (427 aa)
      score_image     score_image   0.850
DIEXF
digestive organ expansion factor homolog (zebrafish); Regulates the p53 pathway to control the expansion growth of digestive organs (By similarity) (756 aa)
      score_image     score_image   0.817
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae); Involved in ribosome biogenesis (By similarity) (365 aa)
      score_image     score_image   0.774
RRP9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast); Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA (475 aa)
      score_image     score_image   0.745
FTSJ3
FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation (847 aa)
      score_image     score_image   0.734
WDR12
WD repeat domain 12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome (423 aa)
      score_image     score_image   0.711
UTP14C
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast); Essential for spermatogenesis. May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis (By similarity) (766 aa)
      score_image         0.704
UTP14A
UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast); May be required for ribosome biogenesis (By similarity) (771 aa)
      score_image         0.704
NGDN
neuroguidin, EIF4E binding protein; Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs (By similarity) (315 aa)
      score_image     score_image   0.702
MAK16
MAK16 homolog (S. cerevisiae) (300 aa)
      score_image     score_image   0.698
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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