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STRINGSTRING
PCDH7 PCDH7 OBSCN OBSCN EIF2B1 EIF2B1 TUFM TUFM SEPSECS SEPSECS GTPBP2 GTPBP2 CWC22 CWC22 ZNF217 ZNF217 KCNK1 KCNK1 DLG5 DLG5 IRF2BP2 IRF2BP2
"GTPBP2" - GTP binding protein 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GTPBP2GTP binding protein 2 (602 aa)    
Predicted Functional Partners:
PCDH7
protocadherin 7 (1255 aa)
            score_image   0.814
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (8678 aa)
        score_image       0.712
EIF2B1
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP (305 aa)
        score_image       0.666
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae); May be involved in pre-mRNA splicing (908 aa)
        score_image       0.666
SEPSECS
Sep (O-phosphoserine) tRNA-Sec (selenocysteine) tRNA synthase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis (501 aa)
        score_image       0.666
DLG5
discs, large homolog 5 (Drosophila) (1919 aa)
        score_image       0.666
KCNK1
potassium channel, subfamily K, member 1; Weakly inward rectifying potassium channel (336 aa)
        score_image       0.666
IRF2BP2
interferon regulatory factor 2 binding protein 2; Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscle (587 aa)
        score_image       0.666
TUFM
Tu translation elongation factor, mitochondrial; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (455 aa)
        score_image     score_image 0.666
ZNF217
zinc finger protein 217; Binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at ’Ser-473’ (1048 aa)
        score_image       0.666
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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