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STRINGSTRING
COL19A1 COL19A1 SLC30A9 SLC30A9 SLC30A5 SLC30A5 TMC7 TMC7 LRRIQ3 LRRIQ3 LRRC66 LRRC66 SAMD5 SAMD5
"TMC7" - transmembrane channel-like 7 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMC7transmembrane channel-like 7; Probable ion channel (By similarity) (723 aa)    
Predicted Functional Partners:
SLC30A9
solute carrier family 30 (zinc transporter), member 9; Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt- responsive genes (By similarity) (568 aa)
            score_image   0.566
SLC30A5
solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP (765 aa)
            score_image   0.550
COL19A1
collagen, type XIX, alpha 1 (1142 aa)
            score_image   0.477
LRRC66
leucine rich repeat containing 66 (880 aa)
            score_image   0.414
SAMD5
sterile alpha motif domain containing 5 (173 aa)
            score_image   0.412
LRRIQ3
leucine-rich repeats and IQ motif containing 3 (624 aa)
            score_image   0.400
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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