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STRINGSTRING
EPPIN EPPIN WFIKKN2 WFIKKN2 ENSG00000249139 ENSG00000249139 FSTL5 FSTL5 CSMD3 CSMD3 GALNTL5 GALNTL5 C15orf53 C15orf53 FAM155A FAM155A
"FSTL5" - follistatin-like 5 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FSTL5follistatin-like 5 (847 aa)    
Predicted Functional Partners:
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2; Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin (By similarity) (576 aa)
            score_image   0.561
C15orf53
chromosome 15 open reading frame 53 (179 aa)
            score_image   0.507
GALNTL5
UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase-like 5; May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor (By similarity) (443 aa)
            score_image   0.503
ENSG00000249139
EPPIN-WFDC6 readthrough (179 aa)
            score_image   0.475
FAM155A
family with sequence similarity 155, member A (458 aa)
            score_image   0.470
CSMD3
CUB and Sushi multiple domains 3 (3707 aa)
            score_image   0.424
EPPIN
epididymal peptidase inhibitor; Serine protease inhibitor that plays an essential role in male reproduction and fertility. Modulates the hydrolysis of SEMG1 by KLK3/PSA (a serine protease), provides antimicrobial protection for spermatozoa in the ejaculate coagulum, and binds SEMG1 thereby inhibiting sperm motility (179 aa)
            score_image   0.409
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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