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ST3GAL3 ST3GAL3 B3GNT3 B3GNT3 B4GALT1 B4GALT1 B3GALT5 B3GALT5 FUT2 FUT2 FUT3 FUT3 ST3GAL6 ST3GAL6 FUT1 FUT1 ST3GAL4 ST3GAL4 GCNT2 GCNT2 B3GNT4 B3GNT4
"FUT3" - fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) in Homo sapiens
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FUT3fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group); May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. May be involved in blood group Lewis determination; Lewis-positive (Le(+)) individuals have an active enzyme while Lewis-negative (Le(-)) individuals have an inactive enzyme. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links (361 aa)    
Predicted Functional Partners:
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group); Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values (365 aa)
           score_image score_image   0.978
FUT2
fucosyltransferase 2 (secretor status included); Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values (343 aa)
           score_image score_image   0.977
ST3GAL3
ST3 beta-galactoside alpha-2,3-sialyltransferase 3 (444 aa)
           score_image score_image   0.942
B3GALT5
UDP-Gal-betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5; Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor (310 aa)
           score_image score_image   0.937
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4; It may catalyze the formation of the NeuAc-alpha-2,3- Gal-beta-1,3-GalNAc- or NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. It may be involved in the biosynthesis of the sialyl Lewis X determinant. Also acts on the corresponding 1,3- galactosyl derivative (329 aa)
           score_image score_image   0.933
B4GALT1
UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (398 aa)
           score_image score_image   0.926
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1 (331 aa)
           score_image score_image   0.922
B3GNT4
UDP-GlcNAc-betaGal beta-1,3-N-acetylglucosaminyltransferase 4; Has a beta-1,3-N-acetylglucosaminyltransferase activity for type 2 oligosaccharides (378 aa)
           score_image score_image   0.916
B3GNT3
UDP-GlcNAc-betaGal beta-1,3-N-acetylglucosaminyltransferase 3; Has a beta-1,3-N-acetylglucosaminyltransferase activity for type 2 oligosaccharides (372 aa)
           score_image score_image   0.915
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group); Branching enzyme that converts linear into branched poly-N-acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development. It is closely associated with the development and maturation of erythroid cells. The expression of the blood group I antigen in erythrocytes is determined by isoform C (402 aa)
           score_image score_image   0.914
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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