Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | MRPL39 | mitochondrial ribosomal protein L39 (353 aa) | ||||||||||||
Predicted Functional Partners:
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 | DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex); The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components- 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (453 aa) |
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0.962 | |||||||||
 | MRPL40 | mitochondrial ribosomal protein L40 (206 aa) |
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0.961 | |||||||||
 | MRPL9 | mitochondrial ribosomal protein L9 (267 aa) |
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0.947 | |||||||||
 | MRPL15 | mitochondrial ribosomal protein L15 (296 aa) |
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0.946 | ||||||||
 | MRPL3 | mitochondrial ribosomal protein L3 (348 aa) |
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0.943 | ||||||||
 | MRPL13 | mitochondrial ribosomal protein L13 (178 aa) |
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0.941 | ||||||||
 | MRPL11 | mitochondrial ribosomal protein L11 (192 aa) |
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0.939 | ||||||||
 | MRPL55 | mitochondrial ribosomal protein L55 (164 aa) |
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0.939 | ||||||||||
 | MRPL19 | mitochondrial ribosomal protein L19 (292 aa) |
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0.937 | |||||||||
 | MRPL24 | mitochondrial ribosomal protein L24 (216 aa) |
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0.937 | ||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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