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STRINGSTRING
SCGB1C1 SCGB1C1 AQP12B AQP12B LCE3E LCE3E GOLGA6L9 GOLGA6L9 KBTBD7 KBTBD7 RBFA RBFA HELT HELT FTSJ2 FTSJ2 EIF5B EIF5B PNPT1 PNPT1 PPP1R8 PPP1R8
"RBFA" - ribosome binding factor A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBFAribosome binding factor A (putative) (343 aa)    
Predicted Functional Partners:
KBTBD7
kelch repeat and BTB (POZ) domain containing 7 (684 aa)
        score_image       0.698
EIF5B
eukaryotic translation initiation factor 5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity) (1220 aa)
            score_image   0.582
FTSJ2
FtsJ RNA methyltransferase homolog 2 (E. coli); Probable methyltransferase (246 aa)
            score_image   0.506
PNPT1
polyribonucleotide nucleotidyltransferase 1; RNA-binding protein implicated in numerous RNA metabolic processes. Hydrolyzes single-stranded polyribonucleotides processively in the 3’-to-5’ direction. Mitochondrial intermembrane factor with RNA-processing exoribonulease activity. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double-stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. Required for correct processing and polyadenylation of mitochondrial mRNAs. Plays a role as a cytoplasmic RNA import factor that mediates the trans [...] (783 aa)
            score_image   0.503
GOLGA6L9
golgin A6 family-like 9 (432 aa)
            score_image   0.501
AQP12B
aquaporin 12B; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity) (307 aa)
            score_image   0.457
HELT
helt bHLH transcription factor; Transcriptional repressor which binds preferentially to the canonical E box sequence 5’-CACGCG-3’ (By similarity) (327 aa)
            score_image   0.436
PPP1R8
protein phosphatase 1, regulatory subunit 8; Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation (351 aa)
            score_image   0.416
SCGB1C1
secretoglobin, family 1C, member 1 (95 aa)
            score_image   0.414
LCE3E
late cornified envelope 3E; Precursors of the cornified envelope of the stratum corneum (92 aa)
            score_image   0.414
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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