NMUR1 protein (Homo sapiens) - STRING network view

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

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Score

NMUR1

neuromedin U receptor 1; Receptor for the neuromedin-U and neuromedin-S neuropeptides (By similarity) (426 aa)

Predicted Functional Partners:

NMU

0.999

NMS

0.986

NTS

0.938

NPS

0.933

NMB

0.932

NPY

0.931

POMC

0.927

MLN

0.925

GAL

0.918

SST

0.918

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAL	MLN	ENSP00000265643	ENSP00000388825	galanin/GMAP prepropeptide; Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion	motilin; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle	0.532
GAL	NMB	ENSP00000265643	ENSP00000378089	galanin/GMAP prepropeptide; Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion	neuromedin B; Stimulates smooth muscle contraction in a manner similar to that of bombesin	0.487
GAL	NMS	ENSP00000265643	ENSP00000366061	galanin/GMAP prepropeptide; Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion	neuromedin S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions (By similarity)	0.918
GAL	NMU	ENSP00000265643	ENSP00000264218	galanin/GMAP prepropeptide; Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion	neuromedin U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder	0.954
GAL	NMUR1	ENSP00000265643	ENSP00000305877	galanin/GMAP prepropeptide; Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion	neuromedin U receptor 1; Receptor for the neuromedin-U and neuromedin-S neuropeptides (By similarity)	0.918
GAL	NPS	ENSP00000265643	ENSP00000381105	galanin/GMAP prepropeptide; Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion	neuropeptide S; Modulates arousal and anxiety. May play an important anorexigenic role. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations (By similarity)	0.879
GAL	NPY	ENSP00000265643	ENSP00000242152	galanin/GMAP prepropeptide; Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion	neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone	0.990
GAL	NTS	ENSP00000265643	ENSP00000256010	galanin/GMAP prepropeptide; Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion	neurotensin; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle	0.813
GAL	POMC	ENSP00000265643	ENSP00000264708	galanin/GMAP prepropeptide; Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion	proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol	0.971
GAL	SST	ENSP00000265643	ENSP00000287641	galanin/GMAP prepropeptide; Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion	somatostatin; Somatostatin inhibits the release of somatotropin	0.981
MLN	GAL	ENSP00000388825	ENSP00000265643	motilin; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle	galanin/GMAP prepropeptide; Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion	0.532
MLN	NMB	ENSP00000388825	ENSP00000378089	motilin; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle	neuromedin B; Stimulates smooth muscle contraction in a manner similar to that of bombesin	0.931
MLN	NMS	ENSP00000388825	ENSP00000366061	motilin; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle	neuromedin S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions (By similarity)	0.910
MLN	NMU	ENSP00000388825	ENSP00000264218	motilin; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle	neuromedin U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder	0.947
MLN	NMUR1	ENSP00000388825	ENSP00000305877	motilin; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle	neuromedin U receptor 1; Receptor for the neuromedin-U and neuromedin-S neuropeptides (By similarity)	0.925
MLN	NPS	ENSP00000388825	ENSP00000381105	motilin; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle	neuropeptide S; Modulates arousal and anxiety. May play an important anorexigenic role. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations (By similarity)	0.956
MLN	NPY	ENSP00000388825	ENSP00000242152	motilin; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle	neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone	0.649
MLN	NTS	ENSP00000388825	ENSP00000256010	motilin; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle	neurotensin; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle	0.980
MLN	POMC	ENSP00000388825	ENSP00000264708	motilin; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle	proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol	0.501
MLN	SST	ENSP00000388825	ENSP00000287641	motilin; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle	somatostatin; Somatostatin inhibits the release of somatotropin	0.813

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