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KCNK2 KCNK2 FGF2 FGF2 FGF13 FGF13 KCNK6 KCNK6 NUDT6 NUDT6 KCNK15 KCNK15 KCNK7 KCNK7 GYG1 GYG1 KCNK1 KCNK1 KCNK9 KCNK9 KCNK3 KCNK3
"NUDT6" - nudix (nucleoside diphosphate linked moiety X)-type motif 6 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
NUDT6nudix (nucleoside diphosphate linked moiety X)-type motif 6; May contribute to the regulation of cell proliferation (316 aa)    
Predicted Functional Partners:
FGF2
fibroblast growth factor 2 (basic) (288 aa)
            score_image   0.885
KCNK3
potassium channel, subfamily K, member 3; pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward (394 aa)
            score_image   0.860
KCNK9
potassium channel, subfamily K, member 9; pH-dependent, voltage-insensitive, background potassium channel protein (374 aa)
            score_image   0.860
FGF13
fibroblast growth factor 13; Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (255 aa)
            score_image   0.856
GYG1
glycogenin 1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase (350 aa)
            score_image   0.829
KCNK2
potassium channel, subfamily K, member 2 (426 aa)
            score_image   0.812
KCNK15
potassium channel, subfamily K, member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel (330 aa)
            score_image   0.758
KCNK7
potassium channel, subfamily K, member 7; Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane (307 aa)
            score_image   0.758
KCNK6
potassium channel, subfamily K, member 6; Exhibits outward rectification in a physiological K(+) gradient and mild inward rectification in symmetrical K(+) conditions (313 aa)
            score_image   0.758
KCNK1
potassium channel, subfamily K, member 1; Weakly inward rectifying potassium channel (336 aa)
            score_image   0.756
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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