MRAP protein (Homo sapiens) - STRING network view

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MRAP

melanocortin 2 receptor accessory protein; Required for MC2R expression in certain cell types, suggesting that it is involved in the processing, trafficking or function of MC2R. May be involved in the intracellular trafficking pathways in adipocyte cells (172 aa)

Predicted Functional Partners:

MC2R

0.989

DDX41

0.885

SLC1A2

0.855

FGF2

0.814

TSPO

0.811

NNT

0.756

MRAP2

0.738

BDNF

0.725

RBFOX3

0.704

MAP2

0.700

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDNF	FGF2	ENSP00000414303	ENSP00000264498	brain-derived neurotrophic factor	fibroblast growth factor 2 (basic)	0.953
BDNF	MAP2	ENSP00000414303	ENSP00000353508	brain-derived neurotrophic factor	microtubule-associated protein 2; The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules	0.659
BDNF	MRAP	ENSP00000414303	ENSP00000306697	brain-derived neurotrophic factor	melanocortin 2 receptor accessory protein; Required for MC2R expression in certain cell types, suggesting that it is involved in the processing, trafficking or function of MC2R. May be involved in the intracellular trafficking pathways in adipocyte cells	0.725
BDNF	RBFOX3	ENSP00000414303	ENSP00000393262	brain-derived neurotrophic factor	RNA binding protein, fox-1 homolog (C. elegans) 3; RNA-binding protein that regulates alternative splicing events (By similarity)	0.754
BDNF	SLC1A2	ENSP00000414303	ENSP00000278379	brain-derived neurotrophic factor	solute carrier family 1 (glial high affinity glutamate transporter), member 2; Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium	0.532
BDNF	TSPO	ENSP00000414303	ENSP00000328973	brain-derived neurotrophic factor	translocator protein (18kDa); Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells (By similarity)	0.725
DDX41	FGF2	ENSP00000422753	ENSP00000264498	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved in pre-mRNA splicing	fibroblast growth factor 2 (basic)	0.481
DDX41	MRAP	ENSP00000422753	ENSP00000306697	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved in pre-mRNA splicing	melanocortin 2 receptor accessory protein; Required for MC2R expression in certain cell types, suggesting that it is involved in the processing, trafficking or function of MC2R. May be involved in the intracellular trafficking pathways in adipocyte cells	0.885
DDX41	TSPO	ENSP00000422753	ENSP00000328973	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved in pre-mRNA splicing	translocator protein (18kDa); Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells (By similarity)	0.981
FGF2	BDNF	ENSP00000264498	ENSP00000414303	fibroblast growth factor 2 (basic)	brain-derived neurotrophic factor	0.953
FGF2	DDX41	ENSP00000264498	ENSP00000422753	fibroblast growth factor 2 (basic)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved in pre-mRNA splicing	0.481
FGF2	MAP2	ENSP00000264498	ENSP00000353508	fibroblast growth factor 2 (basic)	microtubule-associated protein 2; The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules	0.540
FGF2	MRAP	ENSP00000264498	ENSP00000306697	fibroblast growth factor 2 (basic)	melanocortin 2 receptor accessory protein; Required for MC2R expression in certain cell types, suggesting that it is involved in the processing, trafficking or function of MC2R. May be involved in the intracellular trafficking pathways in adipocyte cells	0.814
FGF2	RBFOX3	ENSP00000264498	ENSP00000393262	fibroblast growth factor 2 (basic)	RNA binding protein, fox-1 homolog (C. elegans) 3; RNA-binding protein that regulates alternative splicing events (By similarity)	0.661
FGF2	TSPO	ENSP00000264498	ENSP00000328973	fibroblast growth factor 2 (basic)	translocator protein (18kDa); Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells (By similarity)	0.816
MAP2	BDNF	ENSP00000353508	ENSP00000414303	microtubule-associated protein 2; The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules	brain-derived neurotrophic factor	0.659
MAP2	FGF2	ENSP00000353508	ENSP00000264498	microtubule-associated protein 2; The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules	fibroblast growth factor 2 (basic)	0.540
MAP2	MRAP	ENSP00000353508	ENSP00000306697	microtubule-associated protein 2; The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules	melanocortin 2 receptor accessory protein; Required for MC2R expression in certain cell types, suggesting that it is involved in the processing, trafficking or function of MC2R. May be involved in the intracellular trafficking pathways in adipocyte cells	0.700
MAP2	RBFOX3	ENSP00000353508	ENSP00000393262	microtubule-associated protein 2; The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules	RNA binding protein, fox-1 homolog (C. elegans) 3; RNA-binding protein that regulates alternative splicing events (By similarity)	0.755
MAP2	TSPO	ENSP00000353508	ENSP00000328973	microtubule-associated protein 2; The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules	translocator protein (18kDa); Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells (By similarity)	0.700

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