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STRINGSTRING
C17orf59 C17orf59 KXD1 KXD1 C14orf80 C14orf80 S100P S100P XAGE1D XAGE1D LRRC45 LRRC45 THAP11 THAP11 CROCC CROCC
"LRRC45" - leucine rich repeat containing 45 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRC45leucine rich repeat containing 45 (670 aa)    
Predicted Functional Partners:
S100P
S100 calcium binding protein P; May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE) (95 aa)
        score_image   score_image   0.654
KXD1
KxDL motif containing 1; Involved in endosomal cargo sorting (By similarity) (176 aa)
        score_image       0.597
THAP11
THAP domain containing 11; Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity) (314 aa)
        score_image   score_image   0.563
XAGE1D
X antigen family, member 1D (81 aa)
            score_image   0.536
C17orf59
chromosome 17 open reading frame 59 (357 aa)
            score_image   0.512
CROCC
ciliary rootlet coiled-coil, rootletin; Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Contributes to centrosome cohesion before mitosis (2017 aa)
            score_image   0.504
C14orf80
chromosome 14 open reading frame 80 (426 aa)
            score_image   0.420
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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