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STRINGSTRING
TMEM106B TMEM106B TUBB2A TUBB2A NOC3L NOC3L MAP4 MAP4 MAP6 MAP6 MAP1B MAP1B NAPG NAPG KIAA1383 KIAA1383 KRT16 KRT16 UNC119 UNC119 GPM6A GPM6A
"MAP6" - microtubule-associated protein 6 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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second shell of interactors
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Predicted Interactions
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MAP6microtubule-associated protein 6; Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has microtubule cold stabilizing activity (813 aa)    
Predicted Functional Partners:
UNC119
unc-119 homolog (C. elegans); Myristoyl-binding protein that acts as a cargo adapter- specifically binds the myristoyl moiety of a subset of N- terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G- protein localization and trafficking in sensory neurons. Binds myristoylated NPHP3; however, in contrast to UNC119B, does not seem to play a major role in ciliary membrane localization of NPHP3. Does not bind all myristoylated proteins. Probably plays a role in trafficking proteins in photoreceptor cells (240 aa)
            score_image   0.806
GPM6A
glycoprotein M6A; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type [...] (278 aa)
            score_image   0.805
KRT16
keratin 16 (473 aa)
            score_image   0.800
KIAA1383
KIAA1383; Microtubule-associated protein (MAP) that plays a role in the regulation of cell division; promotes microtubule stability and participates in the organization of the spindle midzone and normal progress of cytokinesis (1047 aa)
            score_image   0.694
TMEM106B
transmembrane protein 106B (274 aa)
        score_image   score_image   0.630
MAP1B
microtubule-associated protein 1B; Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B Binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing (2468 aa)
            score_image   0.608
TUBB2A
tubulin, beta 2A class IIa; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity) (445 aa)
        score_image   score_image   0.601
NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (312 aa)
            score_image   0.601
NOC3L
nucleolar complex associated 3 homolog (S. cerevisiae); May be required for adipogenesis (By similarity) (800 aa)
            score_image   0.595
MAP4
microtubule-associated protein 4; Non-neuronal microtubule-associated protein. Promotes microtubule assembly (1152 aa)
            score_image   0.573
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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