C8orf74 protein (Homo sapiens) - STRING network view

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C8orf74

chromosome 8 open reading frame 74 (294 aa)

Predicted Functional Partners:

PRSS55

0.649

RP1L1

0.533

ITIH5

0.502

ENSG00000258724

0.480

SFMBT2

0.474

TNKS

0.470

ITIH2

0.400

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C8orf74	ENSG00000258724	ENSP00000307129	ENSP00000451145	chromosome 8 open reading frame 74	Transcription factor SOX-7; Uncharacterized protein; cDNA FLJ58508, highly similar to Transcription factor SOX-7	0.480
C8orf74	ITIH2	ENSP00000307129	ENSP00000351190	chromosome 8 open reading frame 74	inter-alpha-trypsin inhibitor heavy chain 2; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes	0.400
C8orf74	ITIH5	ENSP00000307129	ENSP00000256861	chromosome 8 open reading frame 74	inter-alpha-trypsin inhibitor heavy chain family, member 5	0.502
C8orf74	PRSS55	ENSP00000307129	ENSP00000333003	chromosome 8 open reading frame 74	protease, serine, 55; Probable serine protease (By similarity)	0.649
C8orf74	RP1L1	ENSP00000307129	ENSP00000371923	chromosome 8 open reading frame 74	retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity)	0.533
C8orf74	SFMBT2	ENSP00000307129	ENSP00000355109	chromosome 8 open reading frame 74	Scm-like with four mbt domains 2	0.474
C8orf74	TNKS	ENSP00000307129	ENSP00000311579	chromosome 8 open reading frame 74	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase; Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex- poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequ [...]	0.470
ENSG00000258724	C8orf74	ENSP00000451145	ENSP00000307129	Transcription factor SOX-7; Uncharacterized protein; cDNA FLJ58508, highly similar to Transcription factor SOX-7	chromosome 8 open reading frame 74	0.480
ENSG00000258724	RP1L1	ENSP00000451145	ENSP00000371923	Transcription factor SOX-7; Uncharacterized protein; cDNA FLJ58508, highly similar to Transcription factor SOX-7	retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity)	0.756
ITIH2	C8orf74	ENSP00000351190	ENSP00000307129	inter-alpha-trypsin inhibitor heavy chain 2; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes	chromosome 8 open reading frame 74	0.400
ITIH2	SFMBT2	ENSP00000351190	ENSP00000355109	inter-alpha-trypsin inhibitor heavy chain 2; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes	Scm-like with four mbt domains 2	0.483
ITIH5	C8orf74	ENSP00000256861	ENSP00000307129	inter-alpha-trypsin inhibitor heavy chain family, member 5	chromosome 8 open reading frame 74	0.502
ITIH5	SFMBT2	ENSP00000256861	ENSP00000355109	inter-alpha-trypsin inhibitor heavy chain family, member 5	Scm-like with four mbt domains 2	0.561
PRSS55	C8orf74	ENSP00000333003	ENSP00000307129	protease, serine, 55; Probable serine protease (By similarity)	chromosome 8 open reading frame 74	0.649
PRSS55	RP1L1	ENSP00000333003	ENSP00000371923	protease, serine, 55; Probable serine protease (By similarity)	retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity)	0.450
RP1L1	C8orf74	ENSP00000371923	ENSP00000307129	retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity)	chromosome 8 open reading frame 74	0.533
RP1L1	ENSG00000258724	ENSP00000371923	ENSP00000451145	retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity)	Transcription factor SOX-7; Uncharacterized protein; cDNA FLJ58508, highly similar to Transcription factor SOX-7	0.756
RP1L1	PRSS55	ENSP00000371923	ENSP00000333003	retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity)	protease, serine, 55; Probable serine protease (By similarity)	0.450
SFMBT2	C8orf74	ENSP00000355109	ENSP00000307129	Scm-like with four mbt domains 2	chromosome 8 open reading frame 74	0.474
SFMBT2	ITIH2	ENSP00000355109	ENSP00000351190	Scm-like with four mbt domains 2	inter-alpha-trypsin inhibitor heavy chain 2; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes	0.483

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