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STRINGSTRING
DMD DMD LAMA3 LAMA3 UTRN UTRN ITGA6 ITGA6 LAMA2 LAMA2 LAMC1 LAMC1 DAG1 DAG1 LAMA5 LAMA5 ITGB4 ITGB4 LAMB2 LAMB2 NID1 NID1
"LAMB2" - laminin, beta 2 (laminin S) in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Cooccurence
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[Homology]
Score
LAMB2laminin, beta 2 (laminin S); Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components (1798 aa)    
Predicted Functional Partners:
NID1
nidogen 1; Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell- extracellular matrix interactions (1247 aa)
        score_image   score_image   0.976
LAMA3
laminin, alpha 3; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components (3333 aa)
      score_image score_image score_image score_image score_image 0.955
DMD
dystrophin (3685 aa)
          score_image score_image   0.954
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization (895 aa)
          score_image score_image   0.953
LAMA5
laminin, alpha 5; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components (3695 aa)
      score_image score_image score_image score_image score_image 0.953
UTRN
utrophin; May play a role in anchoring the cytoskeleton to the plasma membrane (By similarity) (3433 aa)
          score_image score_image   0.951
LAMA2
laminin, alpha 2; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components (3122 aa)
      score_image score_image score_image score_image score_image 0.950
ITGB4
integrin, beta 4; Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility (1822 aa)
          score_image score_image   0.949
LAMC1
laminin, gamma 1 (formerly LAMB2); Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components (1609 aa)
      score_image score_image score_image score_image score_image 0.949
ITGA6
integrin, alpha 6 (1091 aa)
          score_image score_image   0.946
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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