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STRINGSTRING
SP8 SP8 DLX1 DLX1 GAD1 GAD1 PVALB PVALB SDF4 SDF4 CACNA1A CACNA1A CALB2 CALB2 SST SST BDNF BDNF HTT HTT CA7 CA7
"CALB2" - calbindin 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
CALB2calbindin 2; Calretinin is a calcium-binding protein which is abundant in auditory neurons (271 aa)    
Predicted Functional Partners:
PVALB
parvalbumin; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (110 aa)
            score_image   0.943
BDNF
brain-derived neurotrophic factor (329 aa)
            score_image   0.910
DLX1
distal-less homeobox 1; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions (By similarity) (255 aa)
            score_image   0.896
GAD1
glutamate decarboxylase 1 (brain, 67kDa); Catalyzes the production of GABA (594 aa)
      score_image score_image   score_image   0.862
CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (2506 aa)
        score_image   score_image   0.843
SDF4
stromal cell derived factor 4 (362 aa)
            score_image   0.813
SST
somatostatin; Somatostatin inhibits the release of somatotropin (116 aa)
            score_image   0.810
HTT
huntingtin; May play a role in microtubule-mediated transport or vesicle function (3142 aa)
            score_image   0.808
SP8
Sp8 transcription factor; Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity) (508 aa)
        score_image   score_image   0.780
CA7
carbonic anhydrase VII; Reversible hydration of carbon dioxide (264 aa)
            score_image   0.778
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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