CCDC132 protein (Homo sapiens) - STRING network view

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Score

CCDC132

coiled-coil domain containing 132 (964 aa)

Predicted Functional Partners:

SRPK2

0.508

UBC

0.483

PMFBP1

0.401

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC132	PMFBP1	ENSP00000307666	ENSP00000237353	coiled-coil domain containing 132	polyamine modulated factor 1 binding protein 1; May play a role in sperm morphology especially the sperm tail and consequently affect fertility. May also be involved in the general organization of cellular cytoskeleton	0.401
CCDC132	SRPK2	ENSP00000307666	ENSP00000377262	coiled-coil domain containing 132	SRSF protein kinase 2; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and [...]	0.508
CCDC132	UBC	ENSP00000307666	ENSP00000344818	coiled-coil domain containing 132	ubiquitin C	0.483
PMFBP1	CCDC132	ENSP00000237353	ENSP00000307666	polyamine modulated factor 1 binding protein 1; May play a role in sperm morphology especially the sperm tail and consequently affect fertility. May also be involved in the general organization of cellular cytoskeleton	coiled-coil domain containing 132	0.401
SRPK2	CCDC132	ENSP00000377262	ENSP00000307666	SRSF protein kinase 2; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and [...]	coiled-coil domain containing 132	0.508
SRPK2	UBC	ENSP00000377262	ENSP00000344818	SRSF protein kinase 2; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and [...]	ubiquitin C	0.636
UBC	CCDC132	ENSP00000344818	ENSP00000307666	ubiquitin C	coiled-coil domain containing 132	0.483
UBC	SRPK2	ENSP00000344818	ENSP00000377262	ubiquitin C	SRSF protein kinase 2; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and [...]	0.636

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