FAM90A1 protein (Homo sapiens) - STRING network view

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[Homology]

Score

FAM90A1

family with sequence similarity 90, member A1 (464 aa)

Predicted Functional Partners:

ALG1

0.867

LRLE1

0.634

DEFB105A

0.568

NPIP

0.531

DEFB104A

0.467

SRPK2

0.461

DEFB108B

0.408

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALG1	FAM90A1	ENSP00000262374	ENSP00000307798	asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae); Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER	family with sequence similarity 90, member A1	0.867
DEFB104A	DEFB105A	ENSP00000320813	ENSP00000334330	defensin, beta 104A; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103	defensin, beta 105A; Has antibacterial activity (Potential)	0.728
DEFB104A	DEFB108B	ENSP00000320813	ENSP00000333234	defensin, beta 104A; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103	defensin, beta 108B; Has antibacterial activity (By similarity)	0.564
DEFB104A	FAM90A1	ENSP00000320813	ENSP00000307798	defensin, beta 104A; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103	family with sequence similarity 90, member A1	0.467
DEFB104A	LRLE1	ENSP00000320813	ENSP00000470948	defensin, beta 104A; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103	Liver-related low express protein 1	0.506
DEFB105A	DEFB104A	ENSP00000334330	ENSP00000320813	defensin, beta 105A; Has antibacterial activity (Potential)	defensin, beta 104A; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103	0.728
DEFB105A	DEFB108B	ENSP00000334330	ENSP00000333234	defensin, beta 105A; Has antibacterial activity (Potential)	defensin, beta 108B; Has antibacterial activity (By similarity)	0.666
DEFB105A	FAM90A1	ENSP00000334330	ENSP00000307798	defensin, beta 105A; Has antibacterial activity (Potential)	family with sequence similarity 90, member A1	0.568
DEFB105A	LRLE1	ENSP00000334330	ENSP00000470948	defensin, beta 105A; Has antibacterial activity (Potential)	Liver-related low express protein 1	0.632
DEFB108B	DEFB104A	ENSP00000333234	ENSP00000320813	defensin, beta 108B; Has antibacterial activity (By similarity)	defensin, beta 104A; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103	0.564
DEFB108B	DEFB105A	ENSP00000333234	ENSP00000334330	defensin, beta 108B; Has antibacterial activity (By similarity)	defensin, beta 105A; Has antibacterial activity (Potential)	0.666
DEFB108B	FAM90A1	ENSP00000333234	ENSP00000307798	defensin, beta 108B; Has antibacterial activity (By similarity)	family with sequence similarity 90, member A1	0.408
DEFB108B	LRLE1	ENSP00000333234	ENSP00000470948	defensin, beta 108B; Has antibacterial activity (By similarity)	Liver-related low express protein 1	0.472
FAM90A1	ALG1	ENSP00000307798	ENSP00000262374	family with sequence similarity 90, member A1	asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae); Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER	0.867
FAM90A1	DEFB104A	ENSP00000307798	ENSP00000320813	family with sequence similarity 90, member A1	defensin, beta 104A; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103	0.467
FAM90A1	DEFB105A	ENSP00000307798	ENSP00000334330	family with sequence similarity 90, member A1	defensin, beta 105A; Has antibacterial activity (Potential)	0.568
FAM90A1	DEFB108B	ENSP00000307798	ENSP00000333234	family with sequence similarity 90, member A1	defensin, beta 108B; Has antibacterial activity (By similarity)	0.408
FAM90A1	LRLE1	ENSP00000307798	ENSP00000470948	family with sequence similarity 90, member A1	Liver-related low express protein 1	0.634
FAM90A1	NPIP	ENSP00000307798	ENSP00000331843	family with sequence similarity 90, member A1	nuclear pore complex interacting protein	0.531
FAM90A1	SRPK2	ENSP00000307798	ENSP00000377262	family with sequence similarity 90, member A1	SRSF protein kinase 2; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and [...]	0.461

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