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PLA2G2C PLA2G2C PTDSS1 PTDSS1 PLA2G6 PLA2G6 CEPT1 CEPT1 PTDSS2 PTDSS2 PLA2G2E PLA2G2E PEMT PEMT PISD PISD PLA2G2F PLA2G2F EPT1 EPT1 PLA2G12A PLA2G12A
"PTDSS2" - phosphatidylserine synthase 2 in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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PTDSS2phosphatidylserine synthase 2; Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine (487 aa)    
Predicted Functional Partners:
PEMT
phosphatidylethanolamine N-methyltransferase (236 aa)
           score_image score_image   0.968
PISD
phosphatidylserine decarboxylase (375 aa)
           score_image score_image   0.944
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific); Catalyzes phosphatidylethanolamine biosynthesis from CDP-ethanolamine. It thereby plays a central role in the formation and maintenance of vesicular membranes. Involved in the formation of phosphatidylethanolamine via ’Kennedy’ pathway (397 aa)
           score_image score_image   0.936
CEPT1
choline/ethanolamine phosphotransferase 1; Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP- ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity (416 aa)
           score_image score_image   0.934
PLA2G2C
phospholipase A2, group IIC; Inactive phospholipase (Probable) (150 aa)
           score_image score_image   0.925
PLA2G2F
phospholipase A2, group IIF; PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Hydrolyzes phosphatidylglycerol versus phosphatidylcholine with a 15-fold preference (211 aa)
           score_image score_image   0.917
PTDSS1
phosphatidylserine synthase 1; Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine (473 aa)
           score_image score_image score_image 0.917
PLA2G2E
phospholipase A2, group IIE; PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Has a preference for arachidonic-containing phospholipids (142 aa)
           score_image score_image   0.913
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent); Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F- actin polymerization at the pse [...] (806 aa)
           score_image score_image   0.911
PLA2G12A
phospholipase A2, group XIIA; PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl- phosphatidylcholine or -phosphatidylethanolamine (189 aa)
           score_image score_image   0.908
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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