TRIM40 protein (Homo sapiens) - STRING network view

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TRIM40

tripartite motif containing 40 (229 aa)

Predicted Functional Partners:

ZSCAN23

0.594

TRIM54

0.546

VARS2

0.536

TRIM74

0.507

BSPRY

0.502

DDX46

0.489

SUPV3L1

0.480

DHX32

0.479

HLA-DMB

0.470

DHX36

0.460

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BSPRY	TRIM40	ENSP00000363298	ENSP00000308310	B-box and SPRY domain containing; May regulate epithelial calcium transport by inhibiting TRPV5 activity (By similarity)	tripartite motif containing 40	0.502
BSPRY	TRIM74	ENSP00000363298	ENSP00000285805	B-box and SPRY domain containing; May regulate epithelial calcium transport by inhibiting TRPV5 activity (By similarity)	tripartite motif containing 74	0.450
DDX46	DHX32	ENSP00000346236	ENSP00000284690	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; Plays an essential role in splicing, either prior to, or during splicing A complex formation	DEAH (Asp-Glu-Ala-His) box polypeptide 32	0.572
DDX46	DHX36	ENSP00000346236	ENSP00000417078	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; Plays an essential role in splicing, either prior to, or during splicing A complex formation	DEAH (Asp-Glu-Ala-His) box polypeptide 36; Plays a role in degradation and deadenylation of mRNAs containing in their 3’-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis	0.619
DDX46	SUPV3L1	ENSP00000346236	ENSP00000352678	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; Plays an essential role in splicing, either prior to, or during splicing A complex formation	suppressor of var1, 3-like 1 (S. cerevisiae); Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double-stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5’-to-3’ direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of no [...]	0.616
DDX46	TRIM40	ENSP00000346236	ENSP00000308310	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; Plays an essential role in splicing, either prior to, or during splicing A complex formation	tripartite motif containing 40	0.489
DHX32	DDX46	ENSP00000284690	ENSP00000346236	DEAH (Asp-Glu-Ala-His) box polypeptide 32	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; Plays an essential role in splicing, either prior to, or during splicing A complex formation	0.572
DHX32	TRIM40	ENSP00000284690	ENSP00000308310	DEAH (Asp-Glu-Ala-His) box polypeptide 32	tripartite motif containing 40	0.479
DHX36	DDX46	ENSP00000417078	ENSP00000346236	DEAH (Asp-Glu-Ala-His) box polypeptide 36; Plays a role in degradation and deadenylation of mRNAs containing in their 3’-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; Plays an essential role in splicing, either prior to, or during splicing A complex formation	0.619
DHX36	SUPV3L1	ENSP00000417078	ENSP00000352678	DEAH (Asp-Glu-Ala-His) box polypeptide 36; Plays a role in degradation and deadenylation of mRNAs containing in their 3’-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis	suppressor of var1, 3-like 1 (S. cerevisiae); Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double-stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5’-to-3’ direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of no [...]	0.507
DHX36	TRIM40	ENSP00000417078	ENSP00000308310	DEAH (Asp-Glu-Ala-His) box polypeptide 36; Plays a role in degradation and deadenylation of mRNAs containing in their 3’-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis	tripartite motif containing 40	0.460
HLA-DMB	TRIM40	ENSP00000398890	ENSP00000308310	major histocompatibility complex, class II, DM beta	tripartite motif containing 40	0.470
HLA-DMB	ZSCAN23	ENSP00000398890	ENSP00000289788	major histocompatibility complex, class II, DM beta	zinc finger and SCAN domain containing 23; May be involved in transcriptional regulation	0.499
SUPV3L1	DDX46	ENSP00000352678	ENSP00000346236	suppressor of var1, 3-like 1 (S. cerevisiae); Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double-stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5’-to-3’ direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of no [...]	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; Plays an essential role in splicing, either prior to, or during splicing A complex formation	0.616
SUPV3L1	DHX36	ENSP00000352678	ENSP00000417078	suppressor of var1, 3-like 1 (S. cerevisiae); Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double-stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5’-to-3’ direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of no [...]	DEAH (Asp-Glu-Ala-His) box polypeptide 36; Plays a role in degradation and deadenylation of mRNAs containing in their 3’-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis	0.507
SUPV3L1	TRIM40	ENSP00000352678	ENSP00000308310	suppressor of var1, 3-like 1 (S. cerevisiae); Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double-stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5’-to-3’ direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of no [...]	tripartite motif containing 40	0.480
TRIM40	BSPRY	ENSP00000308310	ENSP00000363298	tripartite motif containing 40	B-box and SPRY domain containing; May regulate epithelial calcium transport by inhibiting TRPV5 activity (By similarity)	0.502
TRIM40	DDX46	ENSP00000308310	ENSP00000346236	tripartite motif containing 40	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; Plays an essential role in splicing, either prior to, or during splicing A complex formation	0.489
TRIM40	DHX32	ENSP00000308310	ENSP00000284690	tripartite motif containing 40	DEAH (Asp-Glu-Ala-His) box polypeptide 32	0.479
TRIM40	DHX36	ENSP00000308310	ENSP00000417078	tripartite motif containing 40	DEAH (Asp-Glu-Ala-His) box polypeptide 36; Plays a role in degradation and deadenylation of mRNAs containing in their 3’-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis	0.460

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