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DNAH9 DNAH9 CCDC114 CCDC114 DNAH11 DNAH11 DYNLL1 DYNLL1 DNAH17 DNAH17 DNAI1 DNAI1 DNAH7 DNAH7 DNALI1 DNALI1 DNAAF1 DNAAF1 DNAI2 DNAI2 DNAH5 DNAH5
"DNAI2" - dynein, axonemal, intermediate chain 2 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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experimentally determined
Predicted Interactions
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textmining
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co-expression
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protein homology
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Score
DNAI2dynein, axonemal, intermediate chain 2; Part of the dynein complex of respiratory cilia (605 aa)    
Predicted Functional Partners:
DNALI1
dynein, axonemal, light intermediate chain 1; May play a dynamic role in flagellar motility (280 aa)
          score_image score_image   0.965
CCDC114
coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) (670 aa)
        score_image score_image score_image   0.959
DNAI1
dynein, axonemal, intermediate chain 1; Part of the dynein complex of respiratory cilia (699 aa)
        score_image score_image score_image score_image 0.959
DNAH5
dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles (4624 aa)
        score_image score_image score_image   0.935
DNAH17
dynein, axonemal, heavy chain 17; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) (4485 aa)
        score_image score_image score_image   0.921
DNAH9
dynein, axonemal, heavy chain 9; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (4486 aa)
        score_image score_image score_image   0.896
DNAH11
dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (4523 aa)
        score_image score_image score_image   0.896
DNAH7
dynein, axonemal, heavy chain 7 (4024 aa)
        score_image score_image score_image   0.892
DYNLL1
dynein, light chain, LC8-type 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (89 aa)
        score_image score_image score_image   0.883
DNAAF1
dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli (725 aa)
            score_image   0.865
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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