node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC114 | DNAAF1 | ENSP00000318429 | ENSP00000367815 | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | 0.544 |
CCDC114 | DNAH11 | ENSP00000318429 | ENSP00000330671 | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) | dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP | 0.701 |
CCDC114 | DNAH17 | ENSP00000318429 | ENSP00000374490 | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) | dynein, axonemal, heavy chain 17; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) | 0.743 |
CCDC114 | DNAH5 | ENSP00000318429 | ENSP00000265104 | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) | dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles | 0.776 |
CCDC114 | DNAH7 | ENSP00000318429 | ENSP00000311273 | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) | dynein, axonemal, heavy chain 7 | 0.751 |
CCDC114 | DNAH9 | ENSP00000318429 | ENSP00000262442 | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) | dynein, axonemal, heavy chain 9; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP | 0.606 |
CCDC114 | DNAI1 | ENSP00000318429 | ENSP00000242317 | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) | dynein, axonemal, intermediate chain 1; Part of the dynein complex of respiratory cilia | 0.925 |
CCDC114 | DNAI2 | ENSP00000318429 | ENSP00000308312 | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) | dynein, axonemal, intermediate chain 2; Part of the dynein complex of respiratory cilia | 0.959 |
CCDC114 | DNALI1 | ENSP00000318429 | ENSP00000296218 | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) | dynein, axonemal, light intermediate chain 1; May play a dynamic role in flagellar motility | 0.821 |
CCDC114 | DYNLL1 | ENSP00000318429 | ENSP00000242577 | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) | dynein, light chain, LC8-type 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures | 0.745 |
DNAAF1 | CCDC114 | ENSP00000367815 | ENSP00000318429 | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) | 0.544 |
DNAAF1 | DNAH11 | ENSP00000367815 | ENSP00000330671 | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP | 0.606 |
DNAAF1 | DNAH5 | ENSP00000367815 | ENSP00000265104 | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles | 0.815 |
DNAAF1 | DNAI1 | ENSP00000367815 | ENSP00000242317 | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | dynein, axonemal, intermediate chain 1; Part of the dynein complex of respiratory cilia | 0.763 |
DNAAF1 | DNAI2 | ENSP00000367815 | ENSP00000308312 | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | dynein, axonemal, intermediate chain 2; Part of the dynein complex of respiratory cilia | 0.865 |
DNAAF1 | DNALI1 | ENSP00000367815 | ENSP00000296218 | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | dynein, axonemal, light intermediate chain 1; May play a dynamic role in flagellar motility | 0.865 |
DNAH11 | CCDC114 | ENSP00000330671 | ENSP00000318429 | dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) | 0.701 |
DNAH11 | DNAAF1 | ENSP00000330671 | ENSP00000367815 | dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | 0.606 |
DNAH11 | DNAH5 | ENSP00000330671 | ENSP00000265104 | dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP | dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles | 0.477 |
DNAH11 | DNAH7 | ENSP00000330671 | ENSP00000311273 | dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP | dynein, axonemal, heavy chain 7 | 0.422 |