node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP5H | PBLD | ENSP00000301587 | ENSP00000308466 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a [...] | phenazine biosynthesis-like protein domain containing | 0.469 |
C10orf35 | PBLD | ENSP00000362376 | ENSP00000308466 | chromosome 10 open reading frame 35 | phenazine biosynthesis-like protein domain containing | 0.570 |
EIF2S1 | FAU | ENSP00000256383 | ENSP00000431822 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction [...] | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | 0.924 |
EIF2S1 | PBLD | ENSP00000256383 | ENSP00000308466 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction [...] | phenazine biosynthesis-like protein domain containing | 0.490 |
EIF2S1 | RPL32 | ENSP00000256383 | ENSP00000380156 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction [...] | ribosomal protein L32 | 0.907 |
EIF2S1 | RPL36A | ENSP00000256383 | ENSP00000404375 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction [...] | ribosomal protein L36a | 0.506 |
FAU | EIF2S1 | ENSP00000431822 | ENSP00000256383 | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction [...] | 0.924 |
FAU | PBLD | ENSP00000431822 | ENSP00000308466 | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | phenazine biosynthesis-like protein domain containing | 0.605 |
FAU | RPL32 | ENSP00000431822 | ENSP00000380156 | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | ribosomal protein L32 | 0.999 |
FAU | RPL36A | ENSP00000431822 | ENSP00000404375 | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | ribosomal protein L36a | 0.991 |
HPGD | PBLD | ENSP00000296522 | ENSP00000308466 | hydroxyprostaglandin dehydrogenase 15-(NAD); Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells | phenazine biosynthesis-like protein domain containing | 0.526 |
PBLD | ATP5H | ENSP00000308466 | ENSP00000301587 | phenazine biosynthesis-like protein domain containing | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a [...] | 0.469 |
PBLD | C10orf35 | ENSP00000308466 | ENSP00000362376 | phenazine biosynthesis-like protein domain containing | chromosome 10 open reading frame 35 | 0.570 |
PBLD | EIF2S1 | ENSP00000308466 | ENSP00000256383 | phenazine biosynthesis-like protein domain containing | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction [...] | 0.490 |
PBLD | FAU | ENSP00000308466 | ENSP00000431822 | phenazine biosynthesis-like protein domain containing | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | 0.605 |
PBLD | HPGD | ENSP00000308466 | ENSP00000296522 | phenazine biosynthesis-like protein domain containing | hydroxyprostaglandin dehydrogenase 15-(NAD); Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells | 0.526 |
PBLD | PCYOX1 | ENSP00000308466 | ENSP00000387654 | phenazine biosynthesis-like protein domain containing | prenylcysteine oxidase 1; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine | 0.624 |
PBLD | RPL32 | ENSP00000308466 | ENSP00000380156 | phenazine biosynthesis-like protein domain containing | ribosomal protein L32 | 0.779 |
PBLD | RPL36A | ENSP00000308466 | ENSP00000404375 | phenazine biosynthesis-like protein domain containing | ribosomal protein L36a | 0.459 |
PBLD | STRAP | ENSP00000308466 | ENSP00000392270 | phenazine biosynthesis-like protein domain containing | serine/threonine kinase receptor associated protein; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. STRAP may play a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein | 0.950 |