GEMIN2 protein (Homo sapiens) - STRING network view

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GEMIN2

gem (nuclear organelle) associated protein 2; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus (280 aa)

Predicted Functional Partners:

SMN1

0.999

DDX20

0.999

SNRPD1

0.999

SNRPD2

0.999

SMN2

0.998

SNRPE

0.998

SNRPG

0.997

SNRPF

0.997

GEMIN6

0.996

GEMIN5

0.995

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX20	GEMIN2	ENSP00000358716	ENSP00000308533	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs	gem (nuclear organelle) associated protein 2; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus	0.999
DDX20	GEMIN5	ENSP00000358716	ENSP00000285873	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs	gem (nuclear organelle) associated protein 5; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. GEMIN5 acts as the snRNA-binding protein of the SMN complex	0.996
DDX20	GEMIN6	ENSP00000358716	ENSP00000281950	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs	gem (nuclear organelle) associated protein 6; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus	0.992
DDX20	SMN1	ENSP00000358716	ENSP00000370083	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs	survival of motor neuron 1, telomeric; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs	0.999
DDX20	SMN2	ENSP00000358716	ENSP00000370119	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs	survival of motor neuron 2, centromeric	0.996
DDX20	SNRPD1	ENSP00000358716	ENSP00000300413	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs	small nuclear ribonucleoprotein D1 polypeptide 16kDa; May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA	0.979
DDX20	SNRPD2	ENSP00000358716	ENSP00000342374	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa; Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity)	0.966
DDX20	SNRPE	ENSP00000358716	ENSP00000400591	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs	small nuclear ribonucleoprotein polypeptide E; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Associated with snRNP U1, U2, U4/U6 and U5	0.970
DDX20	SNRPF	ENSP00000358716	ENSP00000266735	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs	small nuclear ribonucleoprotein polypeptide F; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Associated with snRNP U1, U2, U4/U6 and U5	0.955
DDX20	SNRPG	ENSP00000358716	ENSP00000272348	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs	small nuclear ribonucleoprotein polypeptide G; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Associated with snRNP U1, U2, U4/U6 and U5	0.957
GEMIN2	DDX20	ENSP00000308533	ENSP00000358716	gem (nuclear organelle) associated protein 2; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs	0.999
GEMIN2	GEMIN5	ENSP00000308533	ENSP00000285873	gem (nuclear organelle) associated protein 2; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus	gem (nuclear organelle) associated protein 5; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. GEMIN5 acts as the snRNA-binding protein of the SMN complex	0.995
GEMIN2	GEMIN6	ENSP00000308533	ENSP00000281950	gem (nuclear organelle) associated protein 2; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus	gem (nuclear organelle) associated protein 6; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus	0.996
GEMIN2	SMN1	ENSP00000308533	ENSP00000370083	gem (nuclear organelle) associated protein 2; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus	survival of motor neuron 1, telomeric; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs	0.999
GEMIN2	SMN2	ENSP00000308533	ENSP00000370119	gem (nuclear organelle) associated protein 2; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus	survival of motor neuron 2, centromeric	0.998
GEMIN2	SNRPD1	ENSP00000308533	ENSP00000300413	gem (nuclear organelle) associated protein 2; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus	small nuclear ribonucleoprotein D1 polypeptide 16kDa; May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA	0.999
GEMIN2	SNRPD2	ENSP00000308533	ENSP00000342374	gem (nuclear organelle) associated protein 2; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa; Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity)	0.999
GEMIN2	SNRPE	ENSP00000308533	ENSP00000400591	gem (nuclear organelle) associated protein 2; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus	small nuclear ribonucleoprotein polypeptide E; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Associated with snRNP U1, U2, U4/U6 and U5	0.998
GEMIN2	SNRPF	ENSP00000308533	ENSP00000266735	gem (nuclear organelle) associated protein 2; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus	small nuclear ribonucleoprotein polypeptide F; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Associated with snRNP U1, U2, U4/U6 and U5	0.997
GEMIN2	SNRPG	ENSP00000308533	ENSP00000272348	gem (nuclear organelle) associated protein 2; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus	small nuclear ribonucleoprotein polypeptide G; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Associated with snRNP U1, U2, U4/U6 and U5	0.997

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