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STRINGSTRING
PIK3C2B PIK3C2B ETNK2 ETNK2 PPP1R12B PPP1R12B SYT10 SYT10 GOLT1A GOLT1A SFT2D2 SFT2D2 ENSG00000261576 ENSG00000261576 COG6 COG6 ASNA1 ASNA1 SFT2D1 SFT2D1 SFT2D3 SFT2D3
"GOLT1A" - golgi transport 1A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
GOLT1Agolgi transport 1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex (132 aa)    
Predicted Functional Partners:
SFT2D3
SFT2 domain containing 3; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity) (215 aa)
        score_image       0.824
ASNA1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial); ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane pro [...] (348 aa)
        score_image       0.667
SFT2D1
SFT2 domain containing 1; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity) (159 aa)
        score_image       0.665
SFT2D2
SFT2 domain containing 2; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity) (160 aa)
        score_image       0.665
COG6
component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) (657 aa)
        score_image       0.575
ETNK2
ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity) (386 aa)
            score_image   0.538
SYT10
synaptotagmin X; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity) (523 aa)
            score_image   0.518
PPP1R12B
protein phosphatase 1, regulatory subunit 12B (982 aa)
            score_image   0.488
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta; Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns. Does not phosphorylate PtdIns(4,5)P2. May be involved in EGF and PDGF signaling cascades (1634 aa)
            score_image   0.473
ENSG00000261576
Uncharacterized protein (164 aa)
        score_image       0.463
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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