GLE1 protein (Homo sapiens) - STRING network view

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GLE1

GLE1 RNA export mediator homolog (yeast); Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC) (698 aa)

Predicted Functional Partners:

NUP155

0.993

ENSG00000260537

0.993

DDX19B

0.993

RAE1

0.951

NUP93

0.933

DDX19A

0.933

DDX25

0.932

NXF1

0.900

NUP133

0.895

NUP98

0.881

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX19A	GLE1	ENSP00000306117	ENSP00000308622	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A; ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19 functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins (By similarity)	GLE1 RNA export mediator homolog (yeast); Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC)	0.933
DDX19A	NUP98	ENSP00000306117	ENSP00000316032	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A; ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19 functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins (By similarity)	nucleoporin 98kDa	0.542
DDX19A	NXF1	ENSP00000306117	ENSP00000294172	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A; ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19 functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins (By similarity)	nuclear RNA export factor 1; Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5	0.883
DDX19B	GLE1	ENSP00000288071	ENSP00000308622	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B; ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins	GLE1 RNA export mediator homolog (yeast); Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC)	0.993
DDX19B	NUP98	ENSP00000288071	ENSP00000316032	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B; ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins	nucleoporin 98kDa	0.699
DDX19B	NXF1	ENSP00000288071	ENSP00000294172	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B; ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins	nuclear RNA export factor 1; Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5	0.917
DDX19B	RAE1	ENSP00000288071	ENSP00000360286	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B; ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins	RAE1 RNA export 1 homolog (S. pombe); Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton	0.943
DDX25	GLE1	ENSP00000263576	ENSP00000308622	DEAD (Asp-Glu-Ala-Asp) box helicase 25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity)	GLE1 RNA export mediator homolog (yeast); Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC)	0.932
DDX25	NUP98	ENSP00000263576	ENSP00000316032	DEAD (Asp-Glu-Ala-Asp) box helicase 25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity)	nucleoporin 98kDa	0.554
DDX25	NXF1	ENSP00000263576	ENSP00000294172	DEAD (Asp-Glu-Ala-Asp) box helicase 25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity)	nuclear RNA export factor 1; Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5	0.685
ENSG00000260537	GLE1	ENSP00000454699	ENSP00000308622	Uncharacterized protein	GLE1 RNA export mediator homolog (yeast); Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC)	0.993
ENSG00000260537	NUP98	ENSP00000454699	ENSP00000316032	Uncharacterized protein	nucleoporin 98kDa	0.703
ENSG00000260537	NXF1	ENSP00000454699	ENSP00000294172	Uncharacterized protein	nuclear RNA export factor 1; Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5	0.904
ENSG00000260537	RAE1	ENSP00000454699	ENSP00000360286	Uncharacterized protein	RAE1 RNA export 1 homolog (S. pombe); Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton	0.795
GLE1	DDX19A	ENSP00000308622	ENSP00000306117	GLE1 RNA export mediator homolog (yeast); Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A; ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19 functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins (By similarity)	0.933
GLE1	DDX19B	ENSP00000308622	ENSP00000288071	GLE1 RNA export mediator homolog (yeast); Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B; ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins	0.993
GLE1	DDX25	ENSP00000308622	ENSP00000263576	GLE1 RNA export mediator homolog (yeast); Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC)	DEAD (Asp-Glu-Ala-Asp) box helicase 25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity)	0.932
GLE1	ENSG00000260537	ENSP00000308622	ENSP00000454699	GLE1 RNA export mediator homolog (yeast); Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC)	Uncharacterized protein	0.993
GLE1	NUP133	ENSP00000308622	ENSP00000261396	GLE1 RNA export mediator homolog (yeast); Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC)	nucleoporin 133kDa; Involved in poly(A)+ RNA transport	0.895
GLE1	NUP155	ENSP00000308622	ENSP00000231498	GLE1 RNA export mediator homolog (yeast); Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC)	nucleoporin 155kDa; Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport (By similarity)	0.993

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