node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FAM123C | GPR148 | ENSP00000314914 | ENSP00000308908 | family with sequence similarity 123C; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) | G protein-coupled receptor 148; Orphan receptor | 0.459 |
GPR139 | GPR148 | ENSP00000458791 | ENSP00000308908 | G protein-coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway | G protein-coupled receptor 148; Orphan receptor | 0.602 |
GPR139 | GPR153 | ENSP00000458791 | ENSP00000367125 | G protein-coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway | G protein-coupled receptor 153; Orphan receptor | 0.627 |
GPR139 | GPR162 | ENSP00000458791 | ENSP00000311528 | G protein-coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway | G protein-coupled receptor 162; Orphan receptor | 0.483 |
GPR142 | GPR148 | ENSP00000335158 | ENSP00000308908 | G protein-coupled receptor 142; Orphan receptor | G protein-coupled receptor 148; Orphan receptor | 0.485 |
GPR142 | GPR153 | ENSP00000335158 | ENSP00000367125 | G protein-coupled receptor 142; Orphan receptor | G protein-coupled receptor 153; Orphan receptor | 0.653 |
GPR142 | GPR162 | ENSP00000335158 | ENSP00000311528 | G protein-coupled receptor 142; Orphan receptor | G protein-coupled receptor 162; Orphan receptor | 0.483 |
GPR148 | FAM123C | ENSP00000308908 | ENSP00000314914 | G protein-coupled receptor 148; Orphan receptor | family with sequence similarity 123C; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) | 0.459 |
GPR148 | GPR139 | ENSP00000308908 | ENSP00000458791 | G protein-coupled receptor 148; Orphan receptor | G protein-coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway | 0.602 |
GPR148 | GPR142 | ENSP00000308908 | ENSP00000335158 | G protein-coupled receptor 148; Orphan receptor | G protein-coupled receptor 142; Orphan receptor | 0.485 |
GPR148 | GPR153 | ENSP00000308908 | ENSP00000367125 | G protein-coupled receptor 148; Orphan receptor | G protein-coupled receptor 153; Orphan receptor | 0.628 |
GPR148 | GPR162 | ENSP00000308908 | ENSP00000311528 | G protein-coupled receptor 148; Orphan receptor | G protein-coupled receptor 162; Orphan receptor | 0.593 |
GPR148 | GPR26 | ENSP00000308908 | ENSP00000284674 | G protein-coupled receptor 148; Orphan receptor | G protein-coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP | 0.493 |
GPR148 | GPR83 | ENSP00000308908 | ENSP00000243673 | G protein-coupled receptor 148; Orphan receptor | G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor | 0.427 |
GPR148 | RMI2 | ENSP00000308908 | ENSP00000310356 | G protein-coupled receptor 148; Orphan receptor | RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae); Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. The complex is therefore essential for the stability, localization, and function of complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress- induced nuclear foci and mitotic phosphorylation of BLM | 0.580 |
GPR148 | SLC4A11 | ENSP00000308908 | ENSP00000369399 | G protein-coupled receptor 148; Orphan receptor | solute carrier family 4, sodium borate transporter, member 11; Transporter which plays an important role in sodium- mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sod [...] | 0.562 |
GPR148 | TAAR1 | ENSP00000308908 | ENSP00000275216 | G protein-coupled receptor 148; Orphan receptor | trace amine associated receptor 1; Receptor for trace amines, including beta- phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonine. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained s [...] | 0.565 |
GPR153 | GPR139 | ENSP00000367125 | ENSP00000458791 | G protein-coupled receptor 153; Orphan receptor | G protein-coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway | 0.627 |
GPR153 | GPR142 | ENSP00000367125 | ENSP00000335158 | G protein-coupled receptor 153; Orphan receptor | G protein-coupled receptor 142; Orphan receptor | 0.653 |
GPR153 | GPR148 | ENSP00000367125 | ENSP00000308908 | G protein-coupled receptor 153; Orphan receptor | G protein-coupled receptor 148; Orphan receptor | 0.628 |