node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTG1 | EPB41 | ENSP00000331514 | ENSP00000345259 | actin, gamma 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) | 0.606 |
ACTG1 | RBFOX1 | ENSP00000331514 | ENSP00000309117 | actin, gamma 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | RNA binding protein, fox-1 homolog (C. elegans) 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | 0.610 |
ACTG1 | RBPMS | ENSP00000331514 | ENSP00000340176 | actin, gamma 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | RNA binding protein with multiple splicing; Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C- terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA | 0.654 |
ATXN2 | ATXN2L | ENSP00000366843 | ENSP00000378917 | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | ataxin 2-like | 0.622 |
ATXN2 | RBFOX1 | ENSP00000366843 | ENSP00000309117 | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | RNA binding protein, fox-1 homolog (C. elegans) 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | 0.991 |
ATXN2 | RBPMS | ENSP00000366843 | ENSP00000340176 | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | RNA binding protein with multiple splicing; Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C- terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA | 0.451 |
ATXN2L | ATXN2 | ENSP00000378917 | ENSP00000366843 | ataxin 2-like | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | 0.622 |
ATXN2L | RBFOX1 | ENSP00000378917 | ENSP00000309117 | ataxin 2-like | RNA binding protein, fox-1 homolog (C. elegans) 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | 0.767 |
C1orf94 | RBFOX1 | ENSP00000435634 | ENSP00000309117 | chromosome 1 open reading frame 94 | RNA binding protein, fox-1 homolog (C. elegans) 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | 0.672 |
C1orf94 | RBPMS | ENSP00000435634 | ENSP00000340176 | chromosome 1 open reading frame 94 | RNA binding protein with multiple splicing; Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C- terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA | 0.561 |
CDX1 | RBFOX1 | ENSP00000231656 | ENSP00000309117 | caudal type homeobox 1; Could play a role in the terminal differentiation of the intestine | RNA binding protein, fox-1 homolog (C. elegans) 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | 0.608 |
EPB41 | ACTG1 | ENSP00000345259 | ENSP00000331514 | erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) | actin, gamma 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | 0.606 |
EPB41 | RBFOX1 | ENSP00000345259 | ENSP00000309117 | erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) | RNA binding protein, fox-1 homolog (C. elegans) 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | 0.680 |
EPB41 | RBPMS | ENSP00000345259 | ENSP00000340176 | erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) | RNA binding protein with multiple splicing; Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C- terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA | 0.563 |
RBFOX1 | ACTG1 | ENSP00000309117 | ENSP00000331514 | RNA binding protein, fox-1 homolog (C. elegans) 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | actin, gamma 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | 0.610 |
RBFOX1 | ATXN2 | ENSP00000309117 | ENSP00000366843 | RNA binding protein, fox-1 homolog (C. elegans) 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | 0.991 |
RBFOX1 | ATXN2L | ENSP00000309117 | ENSP00000378917 | RNA binding protein, fox-1 homolog (C. elegans) 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | ataxin 2-like | 0.767 |
RBFOX1 | C1orf94 | ENSP00000309117 | ENSP00000435634 | RNA binding protein, fox-1 homolog (C. elegans) 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | chromosome 1 open reading frame 94 | 0.672 |
RBFOX1 | CDX1 | ENSP00000309117 | ENSP00000231656 | RNA binding protein, fox-1 homolog (C. elegans) 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | caudal type homeobox 1; Could play a role in the terminal differentiation of the intestine | 0.608 |
RBFOX1 | EPB41 | ENSP00000309117 | ENSP00000345259 | RNA binding protein, fox-1 homolog (C. elegans) 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) | 0.680 |