node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DDX54 | FKBP6 | ENSP00000323858 | ENSP00000252037 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors | FK506 binding protein 6, 36kDa | 0.417 |
DDX54 | NIP7 | ENSP00000323858 | ENSP00000254940 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors | nuclear import 7 homolog (S. cerevisiae); Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly | 0.957 |
DDX54 | NOL6 | ENSP00000323858 | ENSP00000297990 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors | nucleolar protein family 6 (RNA-associated) | 0.424 |
DDX54 | NSUN3 | ENSP00000323858 | ENSP00000318986 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors | NOP2/Sun domain family, member 3; May have S-adenosyl-L-methionine-dependent methyl- transferase activity (Potential) | 0.671 |
DDX54 | NSUN4 | ENSP00000323858 | ENSP00000419740 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors | NOP2/Sun domain family, member 4; Involved in mitochondrial ribosome large subunit biogenesis | 0.671 |
DDX54 | NSUN5 | ENSP00000323858 | ENSP00000309126 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors | NOP2/Sun domain family, member 5 | 0.671 |
DDX54 | WDR12 | ENSP00000323858 | ENSP00000261015 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors | WD repeat domain 12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.971 |
FKBP6 | DDX54 | ENSP00000252037 | ENSP00000323858 | FK506 binding protein 6, 36kDa | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors | 0.417 |
FKBP6 | LIMK1 | ENSP00000252037 | ENSP00000336740 | FK506 binding protein 6, 36kDa | LIM domain kinase 1 | 0.584 |
FKBP6 | NIP7 | ENSP00000252037 | ENSP00000254940 | FK506 binding protein 6, 36kDa | nuclear import 7 homolog (S. cerevisiae); Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly | 0.442 |
FKBP6 | NSUN5 | ENSP00000252037 | ENSP00000309126 | FK506 binding protein 6, 36kDa | NOP2/Sun domain family, member 5 | 0.705 |
LIMK1 | FKBP6 | ENSP00000336740 | ENSP00000252037 | LIM domain kinase 1 | FK506 binding protein 6, 36kDa | 0.584 |
LIMK1 | NSUN3 | ENSP00000336740 | ENSP00000318986 | LIM domain kinase 1 | NOP2/Sun domain family, member 3; May have S-adenosyl-L-methionine-dependent methyl- transferase activity (Potential) | 0.527 |
LIMK1 | NSUN4 | ENSP00000336740 | ENSP00000419740 | LIM domain kinase 1 | NOP2/Sun domain family, member 4; Involved in mitochondrial ribosome large subunit biogenesis | 0.527 |
LIMK1 | NSUN5 | ENSP00000336740 | ENSP00000309126 | LIM domain kinase 1 | NOP2/Sun domain family, member 5 | 0.759 |
LIMK1 | PHLPP1 | ENSP00000336740 | ENSP00000262719 | LIM domain kinase 1 | PH domain and leucine rich repeat protein phosphatase 1; Protein phosphatase that mediates dephosphorylation of ’Ser-473’ of AKT1, ’Ser-660’ of PRKCB isoform beta-II and ’Ser- 657’ of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of ’Ser-473’ of AKT1 triggers apoptosis and suppression of tumor growth. Controls the phosphorylation of AKT2 and AKT3 more efficiently than that of AKT1. Dephosphorylation of PRKCA and PRKCB leads [...] | 0.788 |
LIMK1 | PHLPP2 | ENSP00000336740 | ENSP00000348611 | LIM domain kinase 1 | PH domain and leucine rich repeat protein phosphatase 2; Protein phosphatase that mediates dephosphorylation of ’Ser-473’ of AKT1, ’Ser-660’ of PRKCB isoform beta-II and ’Ser- 657’ of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of ’Ser-473’ of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradati [...] | 0.788 |
NIP7 | DDX54 | ENSP00000254940 | ENSP00000323858 | nuclear import 7 homolog (S. cerevisiae); Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors | 0.957 |
NIP7 | FKBP6 | ENSP00000254940 | ENSP00000252037 | nuclear import 7 homolog (S. cerevisiae); Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly | FK506 binding protein 6, 36kDa | 0.442 |
NIP7 | NOL6 | ENSP00000254940 | ENSP00000297990 | nuclear import 7 homolog (S. cerevisiae); Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly | nucleolar protein family 6 (RNA-associated) | 0.680 |