RCE1 protein (Homo sapiens) - STRING network view

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RCE1

RCE1 homolog, prenyl protein protease (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1 (329 aa)

Predicted Functional Partners:

ZMPSTE24

0.996

ICMT

0.995

FNTB

0.953

ENSG00000254673

0.935

UBC

0.902

COG6

0.827

USP17L26

0.772

USP17L24

0.772

USP17L28

0.772

USP17L27

0.772

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COG6	RCE1	ENSP00000397441	ENSP00000309163	component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity)	RCE1 homolog, prenyl protein protease (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1	0.827
ENSG00000254673	FNTB	ENSP00000435061	ENSP00000246166	Uncharacterized protein	farnesyltransferase, CAAX box, beta; Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding	0.974
ENSG00000254673	ICMT	ENSP00000435061	ENSP00000343552	Uncharacterized protein	isoprenylcysteine carboxyl methyltransferase; Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues	0.538
ENSG00000254673	RCE1	ENSP00000435061	ENSP00000309163	Uncharacterized protein	RCE1 homolog, prenyl protein protease (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1	0.935
ENSG00000254673	ZMPSTE24	ENSP00000435061	ENSP00000361845	Uncharacterized protein	zinc metallopeptidase STE24 homolog (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C	0.953
FNTB	ENSG00000254673	ENSP00000246166	ENSP00000435061	farnesyltransferase, CAAX box, beta; Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding	Uncharacterized protein	0.974
FNTB	ICMT	ENSP00000246166	ENSP00000343552	farnesyltransferase, CAAX box, beta; Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding	isoprenylcysteine carboxyl methyltransferase; Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues	0.600
FNTB	RCE1	ENSP00000246166	ENSP00000309163	farnesyltransferase, CAAX box, beta; Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding	RCE1 homolog, prenyl protein protease (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1	0.953
FNTB	UBC	ENSP00000246166	ENSP00000344818	farnesyltransferase, CAAX box, beta; Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding	ubiquitin C	0.638
FNTB	ZMPSTE24	ENSP00000246166	ENSP00000361845	farnesyltransferase, CAAX box, beta; Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding	zinc metallopeptidase STE24 homolog (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C	0.960
ICMT	ENSG00000254673	ENSP00000343552	ENSP00000435061	isoprenylcysteine carboxyl methyltransferase; Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues	Uncharacterized protein	0.538
ICMT	FNTB	ENSP00000343552	ENSP00000246166	isoprenylcysteine carboxyl methyltransferase; Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues	farnesyltransferase, CAAX box, beta; Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding	0.600
ICMT	RCE1	ENSP00000343552	ENSP00000309163	isoprenylcysteine carboxyl methyltransferase; Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues	RCE1 homolog, prenyl protein protease (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1	0.995
ICMT	ZMPSTE24	ENSP00000343552	ENSP00000361845	isoprenylcysteine carboxyl methyltransferase; Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues	zinc metallopeptidase STE24 homolog (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C	0.991
RCE1	COG6	ENSP00000309163	ENSP00000397441	RCE1 homolog, prenyl protein protease (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1	component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity)	0.827
RCE1	ENSG00000254673	ENSP00000309163	ENSP00000435061	RCE1 homolog, prenyl protein protease (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1	Uncharacterized protein	0.935
RCE1	FNTB	ENSP00000309163	ENSP00000246166	RCE1 homolog, prenyl protein protease (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1	farnesyltransferase, CAAX box, beta; Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding	0.953
RCE1	ICMT	ENSP00000309163	ENSP00000343552	RCE1 homolog, prenyl protein protease (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1	isoprenylcysteine carboxyl methyltransferase; Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues	0.995
RCE1	UBC	ENSP00000309163	ENSP00000344818	RCE1 homolog, prenyl protein protease (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1	ubiquitin C	0.902
RCE1	USP17L24	ENSP00000309163	ENSP00000425375	RCE1 homolog, prenyl protein protease (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1	ubiquitin specific peptidase 17-like family member 24	0.772

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