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SLC39A6 SLC39A6 SLC39A8 SLC39A8 SLC39A11 SLC39A11 SLC30A5 SLC30A5 SLC30A7 SLC30A7 SLC30A1 SLC30A1 SLC39A1 SLC39A1 SLC30A4 SLC30A4 SLC39A5 SLC39A5 SLC39A4 SLC39A4 SLC39A14 SLC39A14
"SLC39A1" - solute carrier family 39 (zinc transporter), member 1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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second shell of interactors
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Predicted Interactions
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protein homology
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SLC39A1solute carrier family 39 (zinc transporter), member 1; Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells (324 aa)    
Predicted Functional Partners:
SLC30A1
solute carrier family 30 (zinc transporter), member 1; May be involved in zinc transport out of the cell (507 aa)
       score_image     score_image   0.934
SLC39A4
solute carrier family 39 (zinc transporter), member 4; Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability (By similarity) (647 aa)
         score_image   score_image   0.932
SLC30A5
solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP (765 aa)
       score_image     score_image   0.893
SLC39A14
solute carrier family 39 (zinc transporter), member 14; May mediate cellular uptake of nontransferrin-bound iron (By similarity). Broad-scope metal ion transporter with a preference for zinc uptake (492 aa)
         score_image   score_image   0.884
SLC39A5
solute carrier family 39 (metal ion transporter), member 5; May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Seems to play a central role in controlling organismal zinc status (By similarity) (540 aa)
         score_image   score_image   0.879
SLC39A8
solute carrier family 39 (zinc transporter), member 8; Acts as a zinc-influx transporter (460 aa)
         score_image   score_image   0.873
SLC30A7
solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity) (376 aa)
       score_image     score_image   0.861
SLC30A4
solute carrier family 30 (zinc transporter), member 4; Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment (429 aa)
       score_image     score_image   0.854
SLC39A6
solute carrier family 39 (zinc transporter), member 6; May act as a zinc-influx transporter (755 aa)
         score_image   score_image   0.852
SLC39A11
solute carrier family 39 (metal ion transporter), member 11; May act as a zinc-influx transporter (By similarity) (342 aa)
       score_image score_image   score_image   0.847
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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