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DND1 DND1 TBC1D26 TBC1D26 A1CF A1CF APOBEC3G APOBEC3G APOBEC3F APOBEC3F SAMHD1 SAMHD1 APOBEC3D APOBEC3D UBC UBC APOBEC4 APOBEC4 CDA CDA TCEB1 TCEB1
"APOBEC3F" - apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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fusion edge
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gene co-occurrence
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textmining edge
textmining
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co-expression
homology edge
protein homology
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APOBEC3Fapolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. T [...] (373 aa)    
Predicted Functional Partners:
APOBEC3G
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits potent antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral [...] (384 aa)
        score_image score_image score_image score_image 0.880
APOBEC3D
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. T [...] (386 aa)
          score_image score_image score_image 0.722
A1CF
APOBEC1 complementation factor (594 aa)
          score_image score_image   0.720
UBC
ubiquitin C (685 aa)
        score_image       0.688
DND1
dead end homolog 1 (zebrafish); RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3’ untranslated region (3’-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration ( [...] (353 aa)
            score_image   0.639
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative); Putative C to U editing enzyme whose physiological substrate is not yet known (By similarity) (367 aa)
            score_image   0.582
SAMHD1
SAM domain and HD domain 1; Putative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response. May play a role in mediating proinflammatory responses to TNF-alpha signaling (626 aa)
            score_image   0.485
CDA
cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis (146 aa)
            score_image   0.481
TBC1D26
TBC1 domain family, member 26; May act as a GTPase-activating protein for Rab family protein(s) (Potential) (250 aa)
            score_image   0.473
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C); SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) (112 aa)
            score_image   0.463
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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