node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC34 | CPED1 | ENSP00000330240 | ENSP00000309772 | coiled-coil domain containing 34 | cadherin-like and PC-esterase domain containing 1 | 0.447 |
CCDC34 | KLHDC5 | ENSP00000330240 | ENSP00000370671 | coiled-coil domain containing 34 | kelch domain containing 5; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis | 0.628 |
CCDC34 | LGR4 | ENSP00000330240 | ENSP00000368516 | coiled-coil domain containing 34 | leucine-rich repeat containing G protein-coupled receptor 4; Orphan receptor | 0.463 |
CCDC34 | LIN7C | ENSP00000330240 | ENSP00000278193 | coiled-coil domain containing 34 | lin-7 homolog C (C. elegans); Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may [...] | 0.601 |
CPED1 | CCDC34 | ENSP00000309772 | ENSP00000330240 | cadherin-like and PC-esterase domain containing 1 | coiled-coil domain containing 34 | 0.447 |
CPED1 | FAM3C | ENSP00000309772 | ENSP00000353025 | cadherin-like and PC-esterase domain containing 1 | family with sequence similarity 3, member C; May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition | 0.420 |
CPED1 | FUBP3 | ENSP00000309772 | ENSP00000318177 | cadherin-like and PC-esterase domain containing 1 | far upstream element (FUSE) binding protein 3; May interact with single-stranded DNA from the far- upstream element (FUSE). May activate gene expression | 0.545 |
CPED1 | KLHDC5 | ENSP00000309772 | ENSP00000370671 | cadherin-like and PC-esterase domain containing 1 | kelch domain containing 5; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis | 0.594 |
CPED1 | LGR4 | ENSP00000309772 | ENSP00000368516 | cadherin-like and PC-esterase domain containing 1 | leucine-rich repeat containing G protein-coupled receptor 4; Orphan receptor | 0.445 |
CPED1 | LIN7C | ENSP00000309772 | ENSP00000278193 | cadherin-like and PC-esterase domain containing 1 | lin-7 homolog C (C. elegans); Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may [...] | 0.544 |
CPED1 | PPP6R3 | ENSP00000309772 | ENSP00000377390 | cadherin-like and PC-esterase domain containing 1 | protein phosphatase 6, regulatory subunit 3 | 0.530 |
CPED1 | TNFRSF11A | ENSP00000309772 | ENSP00000465500 | cadherin-like and PC-esterase domain containing 1 | tumor necrosis factor receptor superfamily, member 11a, NFKB activator; Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells | 0.435 |
CPED1 | TNFRSF11B | ENSP00000309772 | ENSP00000297350 | cadherin-like and PC-esterase domain containing 1 | tumor necrosis factor receptor superfamily, member 11b; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis | 0.400 |
CPED1 | WNT16 | ENSP00000309772 | ENSP00000222462 | cadherin-like and PC-esterase domain containing 1 | wingless-type MMTV integration site family, member 16; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity) | 0.457 |
FAM3C | CPED1 | ENSP00000353025 | ENSP00000309772 | family with sequence similarity 3, member C; May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition | cadherin-like and PC-esterase domain containing 1 | 0.420 |
FUBP3 | CPED1 | ENSP00000318177 | ENSP00000309772 | far upstream element (FUSE) binding protein 3; May interact with single-stranded DNA from the far- upstream element (FUSE). May activate gene expression | cadherin-like and PC-esterase domain containing 1 | 0.545 |
FUBP3 | KLHDC5 | ENSP00000318177 | ENSP00000370671 | far upstream element (FUSE) binding protein 3; May interact with single-stranded DNA from the far- upstream element (FUSE). May activate gene expression | kelch domain containing 5; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis | 0.485 |
FUBP3 | LIN7C | ENSP00000318177 | ENSP00000278193 | far upstream element (FUSE) binding protein 3; May interact with single-stranded DNA from the far- upstream element (FUSE). May activate gene expression | lin-7 homolog C (C. elegans); Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may [...] | 0.462 |
FUBP3 | PPP6R3 | ENSP00000318177 | ENSP00000377390 | far upstream element (FUSE) binding protein 3; May interact with single-stranded DNA from the far- upstream element (FUSE). May activate gene expression | protein phosphatase 6, regulatory subunit 3 | 0.450 |
KLHDC5 | CCDC34 | ENSP00000370671 | ENSP00000330240 | kelch domain containing 5; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis | coiled-coil domain containing 34 | 0.628 |