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TNFRSF11A TNFRSF11A FUBP3 FUBP3 PPP6R3 PPP6R3 FAM3C FAM3C LIN7C LIN7C KLHDC5 KLHDC5 CPED1 CPED1 CCDC34 CCDC34 TNFRSF11B TNFRSF11B LGR4 LGR4 WNT16 WNT16
"CPED1" - cadherin-like and PC-esterase domain containing 1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
CPED1cadherin-like and PC-esterase domain containing 1 (1026 aa)    
Predicted Functional Partners:
KLHDC5
kelch domain containing 5; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis (505 aa)
            score_image   0.594
FUBP3
far upstream element (FUSE) binding protein 3; May interact with single-stranded DNA from the far- upstream element (FUSE). May activate gene expression (572 aa)
            score_image   0.545
LIN7C
lin-7 homolog C (C. elegans); Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may [...] (197 aa)
            score_image   0.544
PPP6R3
protein phosphatase 6, regulatory subunit 3 (879 aa)
            score_image   0.530
WNT16
wingless-type MMTV integration site family, member 16; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity) (365 aa)
            score_image   0.457
CCDC34
coiled-coil domain containing 34 (373 aa)
            score_image   0.447
LGR4
leucine-rich repeat containing G protein-coupled receptor 4; Orphan receptor (951 aa)
            score_image   0.445
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator; Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells (616 aa)
            score_image   0.435
FAM3C
family with sequence similarity 3, member C; May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition (227 aa)
            score_image   0.420
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis (401 aa)
            score_image   0.400
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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