node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AARS | ADAT1 | ENSP00000261772 | ENSP00000310015 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | adenosine deaminase, tRNA-specific 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala | 0.816 |
AARS | ADAT2 | ENSP00000261772 | ENSP00000237283 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | adenosine deaminase, tRNA-specific 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity) | 0.413 |
AARS | ADAT3 | ENSP00000261772 | ENSP00000332448 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | adenosine deaminase, tRNA-specific 3 | 0.501 |
AARS | KARS | ENSP00000261772 | ENSP00000325448 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | lysyl-tRNA synthetase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of diadenosine oligophosphate (Ap4A), a signaling molecule involved in the activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA(3)(Lys), th [...] | 0.896 |
AARS | UBC | ENSP00000261772 | ENSP00000344818 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | ubiquitin C | 0.961 |
ADAT1 | AARS | ENSP00000310015 | ENSP00000261772 | adenosine deaminase, tRNA-specific 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | 0.816 |
ADAT1 | ADAT2 | ENSP00000310015 | ENSP00000237283 | adenosine deaminase, tRNA-specific 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala | adenosine deaminase, tRNA-specific 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity) | 0.895 |
ADAT1 | ADAT3 | ENSP00000310015 | ENSP00000332448 | adenosine deaminase, tRNA-specific 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala | adenosine deaminase, tRNA-specific 3 | 0.924 |
ADAT1 | CDA | ENSP00000310015 | ENSP00000364212 | adenosine deaminase, tRNA-specific 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala | cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis | 0.570 |
ADAT1 | CPM | ENSP00000310015 | ENSP00000339157 | adenosine deaminase, tRNA-specific 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala | carboxypeptidase M; Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins | 0.564 |
ADAT1 | KARS | ENSP00000310015 | ENSP00000325448 | adenosine deaminase, tRNA-specific 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala | lysyl-tRNA synthetase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of diadenosine oligophosphate (Ap4A), a signaling molecule involved in the activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA(3)(Lys), th [...] | 0.860 |
ADAT1 | PAPOLG | ENSP00000310015 | ENSP00000238714 | adenosine deaminase, tRNA-specific 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala | poly(A) polymerase gamma; Responsible for the post-transcriptional adenylation of the 3’-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA | 0.545 |
ADAT1 | PRPF39 | ENSP00000310015 | ENSP00000348010 | adenosine deaminase, tRNA-specific 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala | PRP39 pre-mRNA processing factor 39 homolog (S. cerevisiae); Involved in pre-mRNA splicing (By similarity) | 0.564 |
ADAT1 | SRRM1 | ENSP00000310015 | ENSP00000326261 | adenosine deaminase, tRNA-specific 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala | serine/arginine repetitive matrix 1; Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3’-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequen [...] | 0.531 |
ADAT1 | UBC | ENSP00000310015 | ENSP00000344818 | adenosine deaminase, tRNA-specific 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala | ubiquitin C | 0.721 |
ADAT2 | AARS | ENSP00000237283 | ENSP00000261772 | adenosine deaminase, tRNA-specific 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity) | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | 0.413 |
ADAT2 | ADAT1 | ENSP00000237283 | ENSP00000310015 | adenosine deaminase, tRNA-specific 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity) | adenosine deaminase, tRNA-specific 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala | 0.895 |
ADAT2 | ADAT3 | ENSP00000237283 | ENSP00000332448 | adenosine deaminase, tRNA-specific 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity) | adenosine deaminase, tRNA-specific 3 | 0.987 |
ADAT2 | CDA | ENSP00000237283 | ENSP00000364212 | adenosine deaminase, tRNA-specific 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity) | cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis | 0.604 |
ADAT2 | KARS | ENSP00000237283 | ENSP00000325448 | adenosine deaminase, tRNA-specific 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity) | lysyl-tRNA synthetase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of diadenosine oligophosphate (Ap4A), a signaling molecule involved in the activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA(3)(Lys), th [...] | 0.414 |