SLC5A6 protein (Homo sapiens) - STRING network view

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SLC5A6

solute carrier family 5 (sodium-dependent vitamin transporter), member 6; Transports pantothenate, biotin and lipoate in the presence of sodium (635 aa)

Predicted Functional Partners:

HLCS

0.967

ACACB

0.955

ACACA

0.951

PC

0.933

PCCA

0.910

MCCC1

0.910

PCCB

0.909

UBC

0.849

PRODH

0.836

PRODH2

0.836

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACACA	ACACB	ENSP00000344789	ENSP00000341044	acetyl-CoA carboxylase alpha	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	0.999
ACACA	HLCS	ENSP00000344789	ENSP00000338387	acetyl-CoA carboxylase alpha	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase); Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl- CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase	0.995
ACACA	MCCC1	ENSP00000344789	ENSP00000265594	acetyl-CoA carboxylase alpha	methylcrotonoyl-CoA carboxylase 1 (alpha)	0.841
ACACA	PC	ENSP00000344789	ENSP00000377527	acetyl-CoA carboxylase alpha	pyruvate carboxylase; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate	0.638
ACACA	PCCA	ENSP00000344789	ENSP00000365462	acetyl-CoA carboxylase alpha	propionyl CoA carboxylase, alpha polypeptide	0.839
ACACA	PCCB	ENSP00000344789	ENSP00000419027	acetyl-CoA carboxylase alpha	propionyl CoA carboxylase, beta polypeptide	0.758
ACACA	SLC5A6	ENSP00000344789	ENSP00000310208	acetyl-CoA carboxylase alpha	solute carrier family 5 (sodium-dependent vitamin transporter), member 6; Transports pantothenate, biotin and lipoate in the presence of sodium	0.951
ACACA	UBC	ENSP00000344789	ENSP00000344818	acetyl-CoA carboxylase alpha	ubiquitin C	0.922
ACACB	ACACA	ENSP00000341044	ENSP00000344789	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	acetyl-CoA carboxylase alpha	0.999
ACACB	HLCS	ENSP00000341044	ENSP00000338387	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase); Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl- CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase	0.997
ACACB	MCCC1	ENSP00000341044	ENSP00000265594	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	methylcrotonoyl-CoA carboxylase 1 (alpha)	0.824
ACACB	PC	ENSP00000341044	ENSP00000377527	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	pyruvate carboxylase; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate	0.634
ACACB	PCCA	ENSP00000341044	ENSP00000365462	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	propionyl CoA carboxylase, alpha polypeptide	0.826
ACACB	PCCB	ENSP00000341044	ENSP00000419027	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	propionyl CoA carboxylase, beta polypeptide	0.768
ACACB	SLC5A6	ENSP00000341044	ENSP00000310208	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	solute carrier family 5 (sodium-dependent vitamin transporter), member 6; Transports pantothenate, biotin and lipoate in the presence of sodium	0.955
ACACB	UBC	ENSP00000341044	ENSP00000344818	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	ubiquitin C	0.851
HLCS	ACACA	ENSP00000338387	ENSP00000344789	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase); Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl- CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase	acetyl-CoA carboxylase alpha	0.995
HLCS	ACACB	ENSP00000338387	ENSP00000341044	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase); Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl- CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase	acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase	0.997
HLCS	MCCC1	ENSP00000338387	ENSP00000265594	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase); Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl- CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase	methylcrotonoyl-CoA carboxylase 1 (alpha)	0.993
HLCS	PC	ENSP00000338387	ENSP00000377527	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase); Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl- CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase	pyruvate carboxylase; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate	0.991

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