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RUSC2 RUSC2 TBC1D20 TBC1D20 STX5 STX5 GOLGA2 GOLGA2 RAB1B RAB1B RAB8A RAB8A YIPF5 YIPF5 RABGGTB RABGGTB UBC UBC RAB11A RAB11A RAB11B RAB11B
RAB1B, member RAS oncogene family in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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RAB1BRAB1B, member RAS oncogene family; Protein transport. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments (201 aa)    
Predicted Functional Partners:
RAB11B
RAB11B, member RAS oncogene family; GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis (By similarity) (218 aa)
    score_image score_image score_image   score_image score_image 0.990
RAB8A
RAB8A, member RAS oncogene family; May be involved in vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization (207 aa)
    score_image score_image score_image   score_image score_image 0.987
RAB11A
RAB11A, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polariza [...] (216 aa)
    score_image score_image score_image   score_image score_image 0.984
UBC
ubiquitin C (685 aa)
        score_image   score_image   0.974
TBC1D20
TBC1 domain family, member 20; May act as a GTPase-activating protein for Rab family protein(s) (403 aa)
        score_image   score_image   0.974
STX5
syntaxin 5; Mediates endoplasmic reticulum to Golgi transport (By similarity) (355 aa)
        score_image   score_image   0.957
YIPF5
Yip1 domain family, member 5; Plays a role in transport between endoplasmic reticulum and Golgi (257 aa)
      score_image score_image   score_image   0.956
RABGGTB
Rab geranylgeranyltransferase, beta subunit; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively (331 aa)
        score_image   score_image   0.943
GOLGA2
golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure (1002 aa)
        score_image   score_image   0.937
RUSC2
RUN and SH3 domain containing 2 (1516 aa)
        score_image   score_image   0.936
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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