node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BET1 | ENSG00000262633 | ENSP00000222547 | ENSP00000461460 | blocked early in transport 1 homolog (S. cerevisiae); Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity) | Golgi SNAP receptor complex member 2; Uncharacterized protein | 0.991 |
BET1 | GOSR1 | ENSP00000222547 | ENSP00000225724 | blocked early in transport 1 homolog (S. cerevisiae); Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity) | golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an impor [...] | 0.989 |
BET1 | GOSR2 | ENSP00000222547 | ENSP00000225567 | blocked early in transport 1 homolog (S. cerevisiae); Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity) | golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial- Golgi to the trans-Golgi network | 0.977 |
BET1 | SCFD1 | ENSP00000222547 | ENSP00000390783 | blocked early in transport 1 homolog (S. cerevisiae); Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity) | sec1 family domain containing 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity) | 0.977 |
BET1 | SEC22A | ENSP00000222547 | ENSP00000310521 | blocked early in transport 1 homolog (S. cerevisiae); Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity) | SEC22 vesicle trafficking protein homolog A (S. cerevisiae); May be involved in vesicle transport between the ER and the Golgi complex (By similarity) | 0.970 |
BET1 | STX18 | ENSP00000222547 | ENSP00000305810 | blocked early in transport 1 homolog (S. cerevisiae); Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity) | syntaxin 18; Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER | 0.830 |
BET1 | STX5 | ENSP00000222547 | ENSP00000294179 | blocked early in transport 1 homolog (S. cerevisiae); Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity) | syntaxin 5; Mediates endoplasmic reticulum to Golgi transport (By similarity) | 0.999 |
BET1 | VAMP7 | ENSP00000222547 | ENSP00000262640 | blocked early in transport 1 homolog (S. cerevisiae); Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity) | vesicle-associated membrane protein 7; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocy [...] | 0.946 |
BET1 | YKT6 | ENSP00000222547 | ENSP00000223369 | blocked early in transport 1 homolog (S. cerevisiae); Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity) | YKT6 v-SNARE homolog (S. cerevisiae); Vesicular soluble NSF attachment protein receptor (v- SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity | 0.974 |
BET1L | ENSG00000262633 | ENSP00000372210 | ENSP00000461460 | blocked early in transport 1 homolog (S. cerevisiae)-like; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity) | Golgi SNAP receptor complex member 2; Uncharacterized protein | 0.992 |
BET1L | GOSR1 | ENSP00000372210 | ENSP00000225724 | blocked early in transport 1 homolog (S. cerevisiae)-like; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity) | golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an impor [...] | 0.998 |
BET1L | GOSR2 | ENSP00000372210 | ENSP00000225567 | blocked early in transport 1 homolog (S. cerevisiae)-like; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity) | golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial- Golgi to the trans-Golgi network | 0.950 |
BET1L | SCFD1 | ENSP00000372210 | ENSP00000390783 | blocked early in transport 1 homolog (S. cerevisiae)-like; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity) | sec1 family domain containing 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity) | 0.925 |
BET1L | SEC22A | ENSP00000372210 | ENSP00000310521 | blocked early in transport 1 homolog (S. cerevisiae)-like; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity) | SEC22 vesicle trafficking protein homolog A (S. cerevisiae); May be involved in vesicle transport between the ER and the Golgi complex (By similarity) | 0.927 |
BET1L | STX18 | ENSP00000372210 | ENSP00000305810 | blocked early in transport 1 homolog (S. cerevisiae)-like; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity) | syntaxin 18; Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER | 0.711 |
BET1L | STX5 | ENSP00000372210 | ENSP00000294179 | blocked early in transport 1 homolog (S. cerevisiae)-like; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity) | syntaxin 5; Mediates endoplasmic reticulum to Golgi transport (By similarity) | 0.998 |
BET1L | VAMP7 | ENSP00000372210 | ENSP00000262640 | blocked early in transport 1 homolog (S. cerevisiae)-like; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity) | vesicle-associated membrane protein 7; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocy [...] | 0.975 |
BET1L | YKT6 | ENSP00000372210 | ENSP00000223369 | blocked early in transport 1 homolog (S. cerevisiae)-like; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity) | YKT6 v-SNARE homolog (S. cerevisiae); Vesicular soluble NSF attachment protein receptor (v- SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity | 0.997 |
ENSG00000262633 | BET1 | ENSP00000461460 | ENSP00000222547 | Golgi SNAP receptor complex member 2; Uncharacterized protein | blocked early in transport 1 homolog (S. cerevisiae); Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity) | 0.991 |
ENSG00000262633 | BET1L | ENSP00000461460 | ENSP00000372210 | Golgi SNAP receptor complex member 2; Uncharacterized protein | blocked early in transport 1 homolog (S. cerevisiae)-like; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity) | 0.992 |