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TTC8 TTC8 EML5 EML5 KCNJ1 KCNJ1 KCNK10 KCNK10 KCNK4 KCNK4 KCND2 KCND2 TRPM8 TRPM8 KCND3 KCND3 KCNK2 KCNK2 KCNJ16 KCNJ16 KCNJ2 KCNJ2
"KCNK10" - potassium channel, subfamily K, member 10 in Homo sapiens
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KCNK10potassium channel, subfamily K, member 10; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids (543 aa)    
Predicted Functional Partners:
KCNK4
potassium channel, subfamily K, member 4; Voltage insensitive, instantaneous, outwardly rectifying potassium channel. Outward rectification is reversed at high external K(+) concentrations (By similarity) (393 aa)
           score_image score_image score_image 0.907
KCNK2
potassium channel, subfamily K, member 2 (426 aa)
           score_image score_image score_image 0.903
KCND3
potassium voltage-gated channel, Shal-related subfamily, member 3; Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits (655 aa)
             score_image   0.558
EML5
echinoderm microtubule associated protein like 5; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) (1977 aa)
             score_image   0.515
TRPM8
transient receptor potential cation channel, subfamily M, member 8; Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of [...] (1104 aa)
             score_image   0.502
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2; Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits (630 aa)
             score_image   0.501
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by inter [...] (427 aa)
             score_image   0.493
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance (418 aa)
             score_image   0.486
TTC8
tetratricopeptide repeat domain 8 (515 aa)
             score_image   0.479
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1; In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This channel is activated by [...] (391 aa)
             score_image   0.462
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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