Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
UTP14C UTP14C PWP2 PWP2 NOC4L NOC4L UTP14A UTP14A PDCD11 PDCD11 BMS1 BMS1 RRP12 RRP12 NAT10 NAT10 BYSL BYSL DHX37 DHX37 NOP14 NOP14
"DHX37" - DEAH in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHX37DEAH (Asp-Glu-Ala-His) box polypeptide 37 (1157 aa)    
Predicted Functional Partners:
NOP14
NOP14 nucleolar protein homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity) (857 aa)
      score_image score_image   score_image   0.995
NAT10
N-acetyltransferase 10 (GCN5-related); Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division (1025 aa)
      score_image score_image   score_image   0.994
UTP14A
UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast); May be required for ribosome biogenesis (By similarity) (771 aa)
      score_image score_image   score_image   0.992
PWP2
PWP2 periodic tryptophan protein homolog (yeast) (919 aa)
      score_image score_image   score_image   0.992
BYSL
bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos (437 aa)
      score_image score_image   score_image   0.991
BMS1
BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity) (1282 aa)
      score_image score_image   score_image   0.991
PDCD11
programmed cell death 11; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA (1871 aa)
      score_image score_image   score_image   0.989
UTP14C
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast); Essential for spermatogenesis. May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis (By similarity) (766 aa)
      score_image score_image   score_image   0.988
RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae) (1297 aa)
      score_image score_image   score_image   0.988
NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae) (516 aa)
      score_image score_image   score_image   0.984
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: low (24%)