Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
|
Your Input:
|
Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
|||||
 | STOX2 | storkhead box 2 (926 aa) | ||||||||||||
Predicted Functional Partners:
| ||||||||||||||
 | PDZD7 | PDZ domain containing 7 (517 aa) |
 |
0.615 | ||||||||||
 | MAT1A | methionine adenosyltransferase I, alpha; Catalyzes the formation of S-adenosylmethionine from methionine and ATP (By similarity) (395 aa) |
|
0.576 | ||||||||||
 | LZIC | leucine zipper and CTNNBIP1 domain containing (190 aa) |
|
0.569 | ||||||||||
 | CSNK1E | casein kinase 1, epsilon; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation (416 aa) |
|
0.565 | ||||||||||
 | MAT2A | methionine adenosyltransferase II, alpha; Catalyzes the formation of S-adenosylmethionine from methionine and ATP (By similarity) (395 aa) |
|
0.547 | ||||||||||
 | CCAR1 | cell division cycle and apoptosis regulator 1 (1150 aa) |
|
0.517 | ||||||||||
 | SFXN3 | sideroflexin 3; Potential iron transporter (325 aa) |
|
0.472 | ||||||||||
 | SFXN1 | sideroflexin 1; Might be involved in the transport of a component required for iron utilization into or out of the mitochondria (322 aa) |
|
0.456 | ||||||||||
 | FER1L6 | fer-1-like 6 (C. elegans) (1857 aa) |
|
0.410 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
Share
