Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
DOC2A DOC2A QPRT QPRT TMEM187 TMEM187 C16orf54 C16orf54 KCTD13 KCTD13 ZSWIM5 ZSWIM5 ASPHD1 ASPHD1 YPEL3 YPEL3 C16orf92 C16orf92 MPHOSPH10 MPHOSPH10 MRP63 MRP63
"ASPHD1" - aspartate beta-hydroxylase domain containing 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASPHD1aspartate beta-hydroxylase domain containing 1 (390 aa)    
Predicted Functional Partners:
C16orf92
chromosome 16 open reading frame 92 (132 aa)
            score_image   0.722
C16orf54
chromosome 16 open reading frame 54 (224 aa)
            score_image   0.660
DOC2A
double C2-like domains, alpha; Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells (400 aa)
            score_image   0.633
YPEL3
yippee-like 3 (Drosophila); Involved in proliferation and apoptosis in myeloid precursor cells (By similarity) (157 aa)
            score_image   0.539
QPRT
quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA) (297 aa)
            score_image   0.534
KCTD13
potassium channel tetramerisation domain containing 13; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration (329 aa)
            score_image   0.525
MRP63
mitochondrial ribosomal protein 63 (102 aa)
            score_image   0.520
TMEM187
transmembrane protein 187 (261 aa)
            score_image   0.508
MPHOSPH10
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (681 aa)
            score_image   0.506
ZSWIM5
zinc finger, SWIM-type containing 5 (1185 aa)
            score_image   0.490
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: low (31%)