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NRCAM NRCAM NFASC NFASC ACTR1B ACTR1B ANK1 ANK1 DCTN1 DCTN1 SPTBN2 SPTBN2 ACTR1A ACTR1A SPTA1 SPTA1 SPTAN1 SPTAN1 HRAS HRAS NCAM1 NCAM1
"SPTBN2" - spectrin, beta, non-erythrocytic 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Cooccurence
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[Homology]
Score
SPTBN2spectrin, beta, non-erythrocytic 2; Probably plays an important role in neuronal membrane skeleton (2390 aa)    
Predicted Functional Partners:
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (376 aa)
        score_image score_image score_image   0.986
NCAM1
neural cell adhesion molecule 1 (848 aa)
        score_image score_image score_image   0.969
SPTAN1
spectrin, alpha, non-erythrocytic 1 (2477 aa)
        score_image score_image score_image score_image 0.968
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2); Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane (2419 aa)
        score_image score_image score_image score_image 0.961
DCTN1
dynactin 1 (1278 aa)
        score_image score_image     0.954
NFASC
neurofascin (1240 aa)
      score_image   score_image score_image   0.936
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (376 aa)
        score_image score_image score_image   0.928
NRCAM
neuronal cell adhesion molecule; Cell adhesion, ankyrin-binding protein involved in neuron-neuron adhesion. May play a role in the molecular assembly of the nodes of Ranvier (By similarity) (1304 aa)
      score_image   score_image score_image   0.920
HRAS
v-Ha-ras Harvey rat sarcoma viral oncogene homolog; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (189 aa)
          score_image score_image   0.918
ANK1
ankyrin 1, erythrocytic (1897 aa)
      score_image score_image score_image score_image   0.917
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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