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TCF23 TCF23 HADH HADH RIT2 RIT2 OMP OMP RRBP1 RRBP1 DDX3Y DDX3Y FTH1 FTH1 SH3GL1 SH3GL1 ZNF699 ZNF699 EIF2AK1 EIF2AK1 XRN1 XRN1
"ZNF699" - zinc finger protein 699 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
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small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
ZNF699zinc finger protein 699; May be involved in transcriptional regulation (642 aa)    
Predicted Functional Partners:
EIF2AK1
eukaryotic translation initiation factor 2-alpha kinase 1 (630 aa)
            score_image   0.813
FTH1
ferritin, heavy polypeptide 1; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity) (183 aa)
            score_image   0.648
SH3GL1
SH3-domain GRB2-like 1; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity) (368 aa)
            score_image   0.635
OMP
olfactory marker protein; May act as a modulator of the olfactory signal- transduction cascade (163 aa)
            score_image   0.583
RRBP1
ribosome binding protein 1 homolog 180kDa (dog) (977 aa)
            score_image   0.581
HADH
hydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA (331 aa)
            score_image   0.563
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (660 aa)
            score_image   0.563
TCF23
transcription factor 23; Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity) (214 aa)
            score_image   0.558
RIT2
Ras-like without CAAX 2; Binds and exchanges GTP and GDP (By similarity) (217 aa)
        score_image   score_image   0.556
XRN1
5’-3’ exoribonuclease 1; Major 5’-3’ exoribonuclease involved in mRNA decay. Required for the 5’-3’-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) (1706 aa)
      score_image score_image   score_image   0.543
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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