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ATP6C ATP6C HK3 HK3 H6PD H6PD HKDC1 HKDC1 GNPNAT1 GNPNAT1 HK2 HK2 HK1 HK1 GNPDA1 GNPDA1 GPI GPI UBC UBC MPI MPI
"GNPDA1" - glucosamine-6-phosphate deaminase 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
GNPDA1glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) (289 aa)    
Predicted Functional Partners:
GPI
glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons (569 aa)
score_image         score_image score_image   0.971
ATP6C
Uncharacterized protein (152 aa)
score_image     score_image score_image score_image score_image   0.965
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1 (184 aa)
      score_image   score_image score_image   0.932
MPI
mannose phosphate isomerase; Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions (423 aa)
          score_image score_image   0.916
HK1
hexokinase 1 (921 aa)
      score_image   score_image score_image   0.912
HKDC1
hexokinase domain containing 1 (917 aa)
      score_image   score_image     0.907
HK3
hexokinase 3 (white cell) (923 aa)
      score_image   score_image     0.907
HK2
hexokinase 2 (917 aa)
      score_image   score_image     0.907
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase); Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates (791 aa)
score_image           score_image   0.903
UBC
ubiquitin C (685 aa)
        score_image   score_image   0.863
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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