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HDHD2 HDHD2 ENSG00000259131 ENSG00000259131 HAGHL HAGHL HAGH HAGH DTD2 DTD2 DTD1 DTD1 DARS2 DARS2 HDDC3 HDDC3 ETHE1 ETHE1 MBLAC2 MBLAC2 GNPDA1 GNPDA1
"DTD2" - D-tyrosyl-tRNA deacylase 2 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
DTD2D-tyrosyl-tRNA deacylase 2 (putative); Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (Potential) (168 aa)    
Predicted Functional Partners:
DTD1
D-tyrosyl-tRNA deacylase 1; Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) (209 aa)
             score_image   0.734
HDHD2
haloacid dehalogenase-like hydrolase domain containing 2 (259 aa)
         score_image       0.644
ENSG00000259131
metallo-beta-lactamase domain containing 2 (279 aa)
 score_image           score_image   0.559
MBLAC2
metallo-beta-lactamase domain containing 2 (279 aa)
 score_image           score_image   0.559
HDDC3
HD domain containing 3; ppGpp hydrolyzing enzyme involved in starvation response (140 aa)
 score_image           score_image   0.526
GNPDA1
glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) (289 aa)
             score_image   0.478
HAGH
hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (308 aa)
 score_image               0.461
HAGHL
hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential) (282 aa)
 score_image               0.461
DARS2
aspartyl-tRNA synthetase 2, mitochondrial (645 aa)
 score_image               0.461
ETHE1
ethylmalonic encephalopathy 1; Probably plays an important role in metabolic homeostasis in mitochondria. May function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm. Suppresses p53- induced apoptosis by preventing nuclear localization of RELA (254 aa)
 score_image               0.461
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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