| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BAALC | CD34 | ENSP00000312457 | ENSP00000310036 | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | CD34 molecule; Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins | 0.606 |
| BAALC | CEBPA | ENSP00000312457 | ENSP00000427514 | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | CCAAT/enhancer binding protein (C/EBP), alpha; C/EBP is a DNA-binding protein that recognizes two different motifs- the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers | 0.658 |
| BAALC | DNASE1L1 | ENSP00000312457 | ENSP00000014935 | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | deoxyribonuclease I-like 1 | 0.587 |
| BAALC | FLT3 | ENSP00000312457 | ENSP00000241453 | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | fms-related tyrosine kinase 3; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activ [...] | 0.700 |
| BAALC | LRRC4C | ENSP00000312457 | ENSP00000278198 | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | leucine rich repeat containing 4C; May promote neurite outgrowth of developing thalamic neurons | 0.627 |
| BAALC | MN1 | ENSP00000312457 | ENSP00000304956 | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | meningioma (disrupted in balanced translocation) 1; May play a role in tumor suppression | 0.726 |
| BAALC | NPM1 | ENSP00000312457 | ENSP00000296930 | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.700 |
| BAALC | PAMR1 | ENSP00000312457 | ENSP00000278360 | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | peptidase domain containing associated with muscle regeneration 1; May play a role in regeneration of skeletal muscle (By similarity) | 0.626 |
| BAALC | RUNX1 | ENSP00000312457 | ENSP00000300305 | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | runt-related transcription factor 1 | 0.897 |
| BAALC | WT1 | ENSP00000312457 | ENSP00000331327 | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | Wilms tumor 1 | 0.561 |
| CD34 | BAALC | ENSP00000310036 | ENSP00000312457 | CD34 molecule; Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | 0.606 |
| CD34 | CEBPA | ENSP00000310036 | ENSP00000427514 | CD34 molecule; Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins | CCAAT/enhancer binding protein (C/EBP), alpha; C/EBP is a DNA-binding protein that recognizes two different motifs- the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers | 0.471 |
| CD34 | FLT3 | ENSP00000310036 | ENSP00000241453 | CD34 molecule; Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins | fms-related tyrosine kinase 3; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activ [...] | 0.815 |
| CD34 | NPM1 | ENSP00000310036 | ENSP00000296930 | CD34 molecule; Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.567 |
| CD34 | RUNX1 | ENSP00000310036 | ENSP00000300305 | CD34 molecule; Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins | runt-related transcription factor 1 | 0.636 |
| CD34 | WT1 | ENSP00000310036 | ENSP00000331327 | CD34 molecule; Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins | Wilms tumor 1 | 0.566 |
| CEBPA | BAALC | ENSP00000427514 | ENSP00000312457 | CCAAT/enhancer binding protein (C/EBP), alpha; C/EBP is a DNA-binding protein that recognizes two different motifs- the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | 0.658 |
| CEBPA | CD34 | ENSP00000427514 | ENSP00000310036 | CCAAT/enhancer binding protein (C/EBP), alpha; C/EBP is a DNA-binding protein that recognizes two different motifs- the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers | CD34 molecule; Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins | 0.471 |
| CEBPA | FLT3 | ENSP00000427514 | ENSP00000241453 | CCAAT/enhancer binding protein (C/EBP), alpha; C/EBP is a DNA-binding protein that recognizes two different motifs- the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers | fms-related tyrosine kinase 3; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activ [...] | 0.962 |
| CEBPA | MN1 | ENSP00000427514 | ENSP00000304956 | CCAAT/enhancer binding protein (C/EBP), alpha; C/EBP is a DNA-binding protein that recognizes two different motifs- the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers | meningioma (disrupted in balanced translocation) 1; May play a role in tumor suppression | 0.902 |
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