RNASEH1 protein (Homo sapiens) - STRING network view

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gene neighborhood

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Score

RNASEH1

ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (286 aa)

Predicted Functional Partners:

RNASEH2A

0.977

RPP38

0.976

RPP30

0.972

RPP21

0.896

POP5

0.895

POP4

0.868

RPP40

0.868

RPP25

0.868

TRIM39R

0.816

RPA1

0.761

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
POP4	POP5	ENSP00000465213	ENSP00000350098	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae); Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae); Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. Also a component of RNase MRP	0.999
POP4	RNASEH1	ENSP00000465213	ENSP00000313350	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae); Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P	ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	0.868
POP4	RPP21	ENSP00000465213	ENSP00000409799	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae); Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P	ribonuclease P/MRP 21kDa subunit	0.995
POP4	RPP25	ENSP00000465213	ENSP00000317691	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae); Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P	ribonuclease P/MRP 25kDa subunit; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. Also a component of RNase MRP. This subunit binds to RNA	0.999
POP4	RPP30	ENSP00000465213	ENSP00000389182	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae); Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P	ribonuclease P/MRP 30kDa subunit; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends	0.998
POP4	RPP38	ENSP00000465213	ENSP00000367439	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae); Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P	ribonuclease P/MRP 38kDa subunit; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus	0.999
POP4	RPP40	ENSP00000465213	ENSP00000369391	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae); Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P	ribonuclease P/MRP 40kDa subunit; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends	0.881
POP4	TRIM39R	ENSP00000465213	ENSP00000424048	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae); Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P	TRIM39-RPP21 readthrough	0.926
POP5	POP4	ENSP00000350098	ENSP00000465213	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae); Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. Also a component of RNase MRP	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae); Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P	0.999
POP5	RNASEH1	ENSP00000350098	ENSP00000313350	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae); Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. Also a component of RNase MRP	ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	0.895
POP5	RPP21	ENSP00000350098	ENSP00000409799	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae); Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. Also a component of RNase MRP	ribonuclease P/MRP 21kDa subunit	0.970
POP5	RPP25	ENSP00000350098	ENSP00000317691	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae); Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. Also a component of RNase MRP	ribonuclease P/MRP 25kDa subunit; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. Also a component of RNase MRP. This subunit binds to RNA	0.999
POP5	RPP30	ENSP00000350098	ENSP00000389182	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae); Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. Also a component of RNase MRP	ribonuclease P/MRP 30kDa subunit; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends	0.997
POP5	RPP38	ENSP00000350098	ENSP00000367439	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae); Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. Also a component of RNase MRP	ribonuclease P/MRP 38kDa subunit; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus	0.796
POP5	RPP40	ENSP00000350098	ENSP00000369391	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae); Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. Also a component of RNase MRP	ribonuclease P/MRP 40kDa subunit; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends	0.596
POP5	TRIM39R	ENSP00000350098	ENSP00000424048	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae); Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. Also a component of RNase MRP	TRIM39-RPP21 readthrough	0.849
RNASEH1	POP4	ENSP00000313350	ENSP00000465213	ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae); Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P	0.868
RNASEH1	POP5	ENSP00000313350	ENSP00000350098	ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae); Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. Also a component of RNase MRP	0.895
RNASEH1	RNASEH2A	ENSP00000313350	ENSP00000221486	ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	ribonuclease H2, subunit A; Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA-RNA duplexes	0.977
RNASEH1	RPA1	ENSP00000313350	ENSP00000254719	ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	replication protein A1, 70kDa; Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing	0.761

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