ABCF1 protein (Homo sapiens) - STRING network view

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ABCF1

ATP-binding cassette, sub-family F (GCN20), member 1 (845 aa)

Predicted Functional Partners:

ABCD4

0.841

ABCE1

0.828

EIF2AK4

0.827

GNL1

0.777

EPRS

0.724

ABCB8

0.721

ABCA7

0.708

ABCG8

0.697

ABCG5

0.697

ABCA8

0.650

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA7	ABCB8	ENSP00000263094	ENSP00000351717	ATP-binding cassette, sub-family A (ABC1), member 7; Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation	ATP-binding cassette, sub-family B (MDR/TAP), member 8	0.788
ABCA7	ABCD4	ENSP00000263094	ENSP00000349396	ATP-binding cassette, sub-family A (ABC1), member 7; Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation	ATP-binding cassette, sub-family D (ALD), member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm	0.894
ABCA7	ABCE1	ENSP00000263094	ENSP00000296577	ATP-binding cassette, sub-family A (ABC1), member 7; Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation	ATP-binding cassette, sub-family E (OABP), member 1; Antagonizes the binding of 2-5A (5’-phosphorylated 2’,5’-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly	0.512
ABCA7	ABCF1	ENSP00000263094	ENSP00000313603	ATP-binding cassette, sub-family A (ABC1), member 7; Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation	ATP-binding cassette, sub-family F (GCN20), member 1	0.708
ABCA8	ABCD4	ENSP00000269080	ENSP00000349396	ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter	ATP-binding cassette, sub-family D (ALD), member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm	0.637
ABCA8	ABCF1	ENSP00000269080	ENSP00000313603	ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter	ATP-binding cassette, sub-family F (GCN20), member 1	0.650
ABCB8	ABCA7	ENSP00000351717	ENSP00000263094	ATP-binding cassette, sub-family B (MDR/TAP), member 8	ATP-binding cassette, sub-family A (ABC1), member 7; Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation	0.788
ABCB8	ABCD4	ENSP00000351717	ENSP00000349396	ATP-binding cassette, sub-family B (MDR/TAP), member 8	ATP-binding cassette, sub-family D (ALD), member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm	0.784
ABCB8	ABCE1	ENSP00000351717	ENSP00000296577	ATP-binding cassette, sub-family B (MDR/TAP), member 8	ATP-binding cassette, sub-family E (OABP), member 1; Antagonizes the binding of 2-5A (5’-phosphorylated 2’,5’-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly	0.491
ABCB8	ABCF1	ENSP00000351717	ENSP00000313603	ATP-binding cassette, sub-family B (MDR/TAP), member 8	ATP-binding cassette, sub-family F (GCN20), member 1	0.721
ABCD4	ABCA7	ENSP00000349396	ENSP00000263094	ATP-binding cassette, sub-family D (ALD), member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm	ATP-binding cassette, sub-family A (ABC1), member 7; Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation	0.894
ABCD4	ABCA8	ENSP00000349396	ENSP00000269080	ATP-binding cassette, sub-family D (ALD), member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm	ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter	0.637
ABCD4	ABCB8	ENSP00000349396	ENSP00000351717	ATP-binding cassette, sub-family D (ALD), member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm	ATP-binding cassette, sub-family B (MDR/TAP), member 8	0.784
ABCD4	ABCE1	ENSP00000349396	ENSP00000296577	ATP-binding cassette, sub-family D (ALD), member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm	ATP-binding cassette, sub-family E (OABP), member 1; Antagonizes the binding of 2-5A (5’-phosphorylated 2’,5’-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly	0.733
ABCD4	ABCF1	ENSP00000349396	ENSP00000313603	ATP-binding cassette, sub-family D (ALD), member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm	ATP-binding cassette, sub-family F (GCN20), member 1	0.841
ABCD4	ABCG5	ENSP00000349396	ENSP00000260645	ATP-binding cassette, sub-family D (ALD), member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm	ATP-binding cassette, sub-family G (WHITE), member 5; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile	0.674
ABCD4	ABCG8	ENSP00000349396	ENSP00000272286	ATP-binding cassette, sub-family D (ALD), member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm	ATP-binding cassette, sub-family G (WHITE), member 8; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile	0.656
ABCE1	ABCA7	ENSP00000296577	ENSP00000263094	ATP-binding cassette, sub-family E (OABP), member 1; Antagonizes the binding of 2-5A (5’-phosphorylated 2’,5’-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly	ATP-binding cassette, sub-family A (ABC1), member 7; Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation	0.512
ABCE1	ABCB8	ENSP00000296577	ENSP00000351717	ATP-binding cassette, sub-family E (OABP), member 1; Antagonizes the binding of 2-5A (5’-phosphorylated 2’,5’-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly	ATP-binding cassette, sub-family B (MDR/TAP), member 8	0.491
ABCE1	ABCD4	ENSP00000296577	ENSP00000349396	ATP-binding cassette, sub-family E (OABP), member 1; Antagonizes the binding of 2-5A (5’-phosphorylated 2’,5’-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly	ATP-binding cassette, sub-family D (ALD), member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm	0.733

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