node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BICD1 | CLPTM1L | ENSP00000281474 | ENSP00000313854 | bicaudal D homolog 1 (Drosophila); Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | 0.573 |
BICD1 | PIK3C3 | ENSP00000281474 | ENSP00000262039 | bicaudal D homolog 1 (Drosophila); Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex | phosphatidylinositol 3-kinase, catalytic subunit type 3; Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes | 0.681 |
CHRNA3 | CLPTM1L | ENSP00000315602 | ENSP00000313854 | cholinergic receptor, nicotinic, alpha 3 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | 0.568 |
CLPTM1L | BICD1 | ENSP00000313854 | ENSP00000281474 | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | bicaudal D homolog 1 (Drosophila); Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex | 0.573 |
CLPTM1L | CHRNA3 | ENSP00000313854 | ENSP00000315602 | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | cholinergic receptor, nicotinic, alpha 3 (neuronal); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.568 |
CLPTM1L | MRPL47 | ENSP00000313854 | ENSP00000417602 | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | mitochondrial ribosomal protein L47 | 0.644 |
CLPTM1L | PIK3C3 | ENSP00000313854 | ENSP00000262039 | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | phosphatidylinositol 3-kinase, catalytic subunit type 3; Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes | 0.613 |
CLPTM1L | SLC6A18 | ENSP00000313854 | ENSP00000323549 | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | solute carrier family 6, member 18; Functions as a sodium and chloride-dependent neutral amino acid transporter (By similarity) | 0.752 |
CLPTM1L | SLC6A3 | ENSP00000313854 | ENSP00000270349 | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals | 0.598 |
CLPTM1L | SPTAN1 | ENSP00000313854 | ENSP00000361824 | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | spectrin, alpha, non-erythrocytic 1 | 0.644 |
CLPTM1L | TERT | ENSP00000313854 | ENSP00000309572 | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA- dependent extension of 3’-chromosomal termini with the 6- n [...] | 0.762 |
CLPTM1L | UBC | ENSP00000313854 | ENSP00000344818 | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | ubiquitin C | 0.893 |
CLPTM1L | UQCRQ | ENSP00000313854 | ENSP00000367934 | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone | 0.644 |
MRPL47 | CLPTM1L | ENSP00000417602 | ENSP00000313854 | mitochondrial ribosomal protein L47 | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | 0.644 |
MRPL47 | UBC | ENSP00000417602 | ENSP00000344818 | mitochondrial ribosomal protein L47 | ubiquitin C | 0.483 |
PIK3C3 | BICD1 | ENSP00000262039 | ENSP00000281474 | phosphatidylinositol 3-kinase, catalytic subunit type 3; Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes | bicaudal D homolog 1 (Drosophila); Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex | 0.681 |
PIK3C3 | CLPTM1L | ENSP00000262039 | ENSP00000313854 | phosphatidylinositol 3-kinase, catalytic subunit type 3; Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | 0.613 |
PIK3C3 | UBC | ENSP00000262039 | ENSP00000344818 | phosphatidylinositol 3-kinase, catalytic subunit type 3; Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes | ubiquitin C | 0.760 |
SLC6A18 | CLPTM1L | ENSP00000323549 | ENSP00000313854 | solute carrier family 6, member 18; Functions as a sodium and chloride-dependent neutral amino acid transporter (By similarity) | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | 0.752 |
SLC6A3 | CLPTM1L | ENSP00000270349 | ENSP00000313854 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals | CLPTM1-like; Enhances cisplatin-mediated apoptosis, when overexpressed | 0.598 |